Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

564 questions · 589 findings · 155 reviews · Headline outcomes only

No studies found 114 · 19.4%GRADE not reported 15 · 2.5%Very low 179 · 30.4%Low 141 · 23.9%Moderate 110 · 18.7%High 30 · 5.1%

Intervention not reported

Low dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher low dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

Mod dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher mod dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

High dose SSRIs versus placebo Continuous administration · women with premenstrual syndrome

The intervention probably leads to higher high dose SSRIs versus placebo Continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

Pain‐free at 30 mins · adults with cluster headache
1 finding from 1 review

Intervention not reported

Headache relief at 15 mins · adults with cluster headache
1 finding from 1 review

Intervention not reported

At least one AE · adults with cluster headache
1 finding from 1 review

Intervention not reported

Serious AE · adults with cluster headache

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain‐free at 15 mins · adults with cluster headache

It is very uncertain whether the intervention changes pain‐free at 15 mins (very low certainty).

1 finding from 1 review

Intervention not reported

Headache relief at 30 mins · adults with cluster headache
1 finding from 1 review

Intervention not reported

Headache relief at 15 mins · adults with cluster headache

It is very uncertain whether the intervention changes headache relief at 15 mins (very low certainty).

1 finding from 1 review

Intervention not reported

At least one AE · adults with cluster headache

It is very uncertain whether the intervention changes at least one AE (very low certainty).

1 finding from 1 review

Intervention not reported

Serious AE · adults with cluster headache

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain‐free at 30 mins · adults with cluster headache

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain‐free at 15 mins · adults with cluster headache
1 finding from 1 review

Intervention not reported

Headache relief at 30 mins · adults with cluster headache

The review found no eligible studies for this question.

1 finding from 1 review