Cochrane · systematic review · CD008042

Triptans for acute cluster headache

Law, S, Derry, S, Moore, RA · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
8
No studies
4
Included studies
NR
No studies 4 · 33.3%Ungraded 0 · 0%Very low 4 · 33.3%Low 4 · 33.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: adults with cluster headache
6 questions
OutcomeEffectEvidenceStatus / GRADE
Pain‐free at 30 mins
no estimate extractedNRLow
Downgraded: imprecision, publication bias
Pain‐free at 15 mins
RR 2.6 [0.8, 8.5]NRVery low
Downgraded: imprecision, publication bias
Headache relief at 30 mins
no estimate extractedNRLow
Downgraded: imprecision, publication bias
Headache relief at 15 mins
RR 2.2 [0.99, 4.67]NRVery low
Downgraded: imprecision, publication bias
At least one AE
RR 1.8 [1.2, 2.8]NRVery low
Downgraded: imprecision, publication bias
Serious AE
no estimate extractedNRNo studies

Comparison

Population: adults with cluster headache
6 questions
OutcomeEffectEvidenceStatus / GRADE
Pain‐free at 30 mins
no estimate extractedNRNo studies
Pain‐free at 15 mins
no estimate extractedNRLow
Downgraded: imprecision, publication bias
Headache relief at 30 mins
no estimate extractedNRNo studies
Headache relief at 15 mins
no estimate extractedNRLow
Downgraded: imprecision, publication bias
At least one AE
no estimate extractedNRVery low
Downgraded: imprecision, publication bias
Serious AE
no estimate extractedNRNo studies