side‐effects ‐ side‐effects causing abandon · prevention of reintubation
The review found no eligible studies for this question.
2 findings from 1 review
Positive‐pressure ventilation after institution of treatment · treatment of apnea
It is very uncertain whether doxapram changes 2a. Need for positive pressure ventilation after initiation of… compared with no treatment, placebo, methylxanthine (including theophylline,… (very low certainty).
3 findings from 1 review
Chronic lung disease · treatment of apnea
The review found no eligible studies for this question.
3 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Serious adverse events or adverse events Death due to methadone use · individuals dependent on illicit opiates
1 finding from 1 review
Bone metastases · women with advanced breast cancer without bone metastases
Bisphosphonates showed no clear difference in bone metastases compared with placebo/observation (moderate certainty).
1 finding from 1 review
Live birth · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)
Intentional endometrial injury showed no clear difference in live birth (primary analysis) compared with no intervention or a sham procedure (low certainty).
1 finding from 1 review
Live birth or ongoing pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)
It is very uncertain whether intentional endometrial injury changes live birth or ongoing pregnancy (sensitivity analysis) compared with no intervention or a sham procedure (very low certainty).
1 finding from 1 review
Clinical pregnancy · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)
2 findings from 1 review
Pain during procedure ‐ not measured · infertile women or couples attempting to conceive through sexual intercourse or intrauterine insemination (IUI)
1 finding from 1 review
Effectiveness Proportion of women with perception of improvement of bleeding symptoms · heavy menstrual bleeding
Endometrial resection/ablation may leads to lower effectiveness Proportion of women with perception of improvement of… compared with unspecified (or at surgeon's discretion) route of hysterectomy (low certainty).
1 finding from 1 review
Quality of life SF‐36 at 2 years – general health perception · heavy menstrual bleeding
1 finding from 1 review
Proportion with improvement in general health · heavy menstrual bleeding
Endometrial resection/ablation may leads to lower proportion with improvement in general health compared with unspecified (or at surgeon's discretion) route of hysterectomy (low certainty).
1 finding from 1 review
Requirement for further surgery for treatment failure · heavy menstrual bleeding
1 finding from 1 review
Acceptability Proportion satisfied with treatment · heavy menstrual bleeding
Endometrial resection/ablation showed no clear difference in acceptability Proportion satisfied with treatment compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).
1 finding from 1 review
Safety Any serious adverse event · heavy menstrual bleeding
Endometrial resection/ablation probably leads to lower safety Any serious adverse event compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).
1 finding from 1 review
Return to normal activity · heavy menstrual bleeding
1 finding from 1 review
Overall survival (absolute effect size estimates based on survival rate at 24 months)
Bacillus Calmette‐Guérin (BCG) showed no clear difference in time to death from any cause (absolute effect size estimates based… compared with mitomycin C (MMC) (low certainty).
1 finding from 1 review
Serious adverse effects
Bacillus Calmette‐Guérin (BCG) showed no clear difference in serious adverse effects compared with mitomycin C (MMC) (low certainty).
1 finding from 1 review
Time to recurrence
Bacillus Calmette‐Guérin (BCG) showed no clear difference in time to recurrence (absolute effect size estimates based on event… compared with mitomycin C (MMC) (low certainty).
1 finding from 1 review
Time to progression
Bacillus Calmette‐Guérin (BCG) showed no clear difference in time to progression (absolute effect size estimates based on event… compared with mitomycin C (MMC) (low certainty).
1 finding from 1 review