Intervention not reported
PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation
The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).
1 finding from 1 review
Intervention not reported
Poor neurological outcome by 28 days' postnatal age · neonates requiring intubation and ventilation
The intervention showed no clear difference in poor neurological outcome by 28 days' postnatal age (moderate certainty).
1 finding from 1 review
Intervention not reported
PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation
The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).
1 finding from 1 review
Intervention not reported
Poor neurological outcome by 28 days' postnatal age · neonates requiring intubation and ventilation
The intervention probably leads to higher poor neurological outcome by 28 days' postnatal age (moderate certainty).
1 finding from 1 review
Intervention not reported
Mortality · people with severe traumatic brain injury (adults and children)
1 finding from 1 review
Intervention not reported
Intracranial pressure (ICP) · people with severe traumatic brain injury (adults and children)
1 finding from 1 review
Intervention not reported
Cerebral perfusion pressure (CPP) · people with severe traumatic brain injury (adults and children)
1 finding from 1 review
Intervention not reported
Quality of life; Glasgow Coma Score; Disability · people with severe traumatic brain injury (adults and children)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Adverse events · people with severe traumatic brain injury (adults and children)
1 finding from 1 review
Weight (g) at 4 months · preterm or low birth weight infants undergoing hospital care
1 finding from 1 review
Length of stay (days) (CL from 32 weeks' PMA) · preterm or low birth weight infants undergoing hospital care
1 finding from 1 review
Length of stay (days) (CL from birth) · preterm or low birth weight infants undergoing hospital care
1 finding from 1 review
Days on ventilator · preterm or low birth weight infants undergoing hospital care
1 finding from 1 review
Intervention not reported
Functional exercise capacity Multiple different outcome measures used SF‐36 PF and AT (at 9 and 26 weeks) (Batterham 2014) SF‐36 PF and 6MWT (at 8 and 26 weeks) (Elliott 2011) ABC, Katz, TUAG (at 3 months) (Jackson 2012) SF‐36 PCS ( · adult survivors of critical illness
1 finding from 1 review
Intervention not reported
Health‐related quality of life Multiple different outcome measures used EQ‐5D and EQ‐5D VAS (9 and 26 weeks) (Batterham 2014) SF‐36 PCS and MCS (8 and 26 weeks) (Elliott 2011) · adult survivors of critical illness
1 finding from 1 review
Intervention not reported
Withdrawals Participant withdrawal following randomization before or during receipt of the intervention because of consent or medical reason · adult survivors of critical illness
1 finding from 1 review
Intervention not reported
Adherence Participant completion of the intervention as described in the trial method · adult survivors of critical illness
1 finding from 1 review
Intervention not reported
Mortality Death at any point during the trial duration · adult survivors of critical illness
1 finding from 1 review
Intervention not reported
Loss to · adult survivors of critical illness
1 finding from 1 review
Intervention not reported
Other adverse events Non‐mortality · adult survivors of critical illness
1 finding from 1 review