Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

573 questions · 608 findings · 115 reviews

No studies found 136 · 22.4%GRADE not reported 54 · 8.9%Very low 166 · 27.3%Low 152 · 25%Moderate 75 · 12.3%High 25 · 4.1%

Intervention not reported

PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation

The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).

1 finding from 1 review

Intervention not reported

Poor neurological outcome by 28 days' postnatal age · neonates requiring intubation and ventilation

The intervention showed no clear difference in poor neurological outcome by 28 days' postnatal age (moderate certainty).

1 finding from 1 review

Intervention not reported

PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation

The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).

1 finding from 1 review

Intervention not reported

Functional exercise capacity Multiple different outcome measures used SF‐36 PF and AT (at 9 and 26 weeks) (Batterham 2014) SF‐36 PF and 6MWT (at 8 and 26 weeks) (Elliott 2011) ABC, Katz, TUAG (at 3 months) (Jackson 2012) SF‐36 PCS ( · adult survivors of critical illness
1 finding from 1 review