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Evidence found and GRADE certainty

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

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No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Scalp block vs placebo or control

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

It is very uncertain whether scalp block changes adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo intervention (very low certainty).

1 finding from 1 review

Supplemental IV crystalloid vs control IV crystalloid volume

Nausea · participants aged 6 months or older undergoing surgical procedures under general anaesthesia

Supplemental IV crystalloid probably leads to lower risk of PON, defined as the presence of subjective nausea, reported… compared with control IV crystalloid volume (moderate certainty).

1 finding from 1 review

Supplemental IV crystalloid vs control IV crystalloid volume

Risk of POV, reported dichotomously by any discrete episodes of vomiting · participants aged 6 months or older undergoing surgical procedures under general anaesthesia

Supplemental IV crystalloid probably leads to lower risk of POV, reported dichotomously by any discrete episodes of… compared with control IV crystalloid volume (moderate certainty).

1 finding from 1 review

Supplemental IV crystalloid vs control IV crystalloid volume

Risk of requiring pharmacologic treatment for PONV, reported dichotomously as the use of any medication intended to treat nausea or vomiting during the postoperative period · participants aged 6 months or older undergoing surgical procedures under general anaesthesia

Supplemental IV crystalloid probably leads to lower risk of requiring pharmacologic treatment for PONV, reported… compared with control IV crystalloid volume (moderate certainty).

1 finding from 1 review

Supplemental IV crystalloid vs control IV crystalloid volume

Risk of unintended postoperative admission to hospital, reported dichotomously as admission to an inpatient unit of a participant after an intended ambulatory surgical procedure · participants aged 6 months or older undergoing surgical procedures under general anaesthesia

Supplemental IV crystalloid showed no clear difference in risk of unintended postoperative admission to hospital, reported… compared with control IV crystalloid volume (low certainty).

1 finding from 1 review

Supplemental IV crystalloid vs control IV crystalloid volume

Risk of suffering a serious adverse event, reported dichotomously as the occurrence of any of: admission to high‐dependency unit, postoperative cardiac or respiratory complication, or death · participants aged 6 months or older undergoing surgical procedures under general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review