Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Multi‐modal hand therapy vs normal activities and advice

Return to normal occupations ‐ 4 weeks after completion of treatment (6 weeks post surgery) · people who have had carpal tunnel release surgery

Multi‐modal hand therapy showed no clear difference in return to normal occupations ‐ at the end of treatment (2 weeks post… compared with normal activities and advice (low certainty).

3 findings from 1 review

Behavioural intervention vs control

Smoking cessation at time of surgery ‐ Intensive behavioural intervention (multiple contacts, initiated at least 4 weeks before surgery) · People awaiting surgery

Behavioural intervention probably leads to higher smoking cessation at time of surgery ‐ Intensive behavioural… compared with control (moderate certainty).

1 finding from 1 review

Behavioural intervention vs control

Smoking cessation at time of surgery ‐ Brief behavioural intervention · People awaiting surgery

Behavioural intervention leads to higher smoking cessation at time of surgery ‐ Brief behavioural intervention compared with control (high certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

The proportion of pressure ulcers healed · people with venous leg ulcers

Subfascial endoscopic perforator vein surgery (SEPS) + compression may leads to higher proportion with ulcers healed at 24 months compared with compression alone (low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Recurrence of ulcers · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + compression changes ulcer recurrence at 24 months compared with compression alone (very low certainty).

1 finding from 1 review