Intravenous/intramuscular ergot alkaloids may leads to higher elevation of blood pressure compared with no uterotonic agents (low certainty).
Intravenous/intramuscular ergot alkaloids probably leads to higher pain after birth requiring analgesia (not prespecified) compared with no uterotonic agents (moderate certainty).
Oral ergot alkaloids showed no clear difference in estimated or measured blood loss of at least 500 mL visual estimation compared with no uterotonic agents (low certainty).
Oral ergot alkaloids showed no clear difference in estimated or measured blood loss of at least 1000 mL visual estimation compared with no uterotonic agents (low certainty).
The review found no eligible studies for this question.
Oral ergot alkaloids showed no clear difference in use of therapeutic uterotonics compared with no uterotonic agents (low certainty).
Ergot alkaloids (any route of administration) may leads to lower PPH (estimated or measured blood loss of at least 500 mL) visual… compared with no uterotonic agents (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
It is very uncertain whether ergot alkaloids (any route of administration) changes severe PPH (estimated or measured blood loss of at least 1000 mL)… compared with no uterotonic agents (very low certainty).
Ergot alkaloids (any route of administration) may leads to lower use of therapeutic uterotonics compared with no uterotonic agents (low certainty).
Ergot alkaloids (any route of administration) may leads to higher elevation of blood pressure compared with no uterotonic agents (low certainty).
Ergot alkaloids (any route of administration) probably leads to higher pain after birth requiring analgesia (not prespecified) compared with no uterotonic agents (moderate certainty).
Intravenous/intramuscular ergot alkaloids may leads to lower estimated or measured blood loss of at least 500 mL visual estimation compared with no uterotonic agents (low certainty).
Intramuscular vitamin K showed no clear difference in bleeding complications: 0.2 mg IV versus 0.2 mg IM compared with intravenous vitamin K (low certainty).
Intramuscular vitamin K showed no clear difference in necrotizing enterocolitis: 0.2 mg IV versus 0.5 mg IM compared with intravenous vitamin K (low certainty).
Intramuscular vitamin K showed no clear difference in sepsis: 0.2 mg IV versus 0.2 mg IM compared with intravenous vitamin K (low certainty).