Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

624 questions · 782 findings · 62 reviews

No studies found 13 · 1.7%GRADE not reported 657 · 84%Very low 76 · 9.7%Low 23 · 2.9%Moderate 13 · 1.7%High 0 · 0%

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Number of teeth · Adults (general and hospital populations assessed in case-control studies)

No statistically significant difference in number of teeth between SSc patients and controls (SMD -0.95, CI includes 0); certainty ungraded.

1 finding from 1 review

Dental caries assessment (WHO/clinical diagnostic criteria; caries = DMFT>0) vs None (descriptive prevalence review; subgroup analyses by urban/rural status, country and year)

Dental caries prevalence · Healthy children and adolescents in the United Arab Emirates

Dental caries is highly prevalent among children and adolescents in the UAE, ranging from 22% to 99.4% across cross-sectional studies (narrative synthesis; not GRADE-rated).

1 finding from 1 review

Systemic sclerosis (SSc / scleroderma) vs SSc-free individuals (controls)

Mean number of missing teeth in OC cases vs controls · Adults (general and hospital populations assessed in case-control studies)

No statistically significant difference in number of missing teeth between SSc patients and controls (SMD 0.55, CI includes 0); certainty ungraded.

1 finding from 1 review

Clear aligners (Invisalign / thermoformed aligners) vs Fixed appliances

Lesion area (decalcification area, pixels) · Adults undergoing orthodontic treatment

A single study reported a larger decalcification lesion area with aligners versus fixed appliances in adults at 3 months (MD 80.50 pixels, 95% CI 60.52 to 100.48; ungraded).

1 finding from 1 review