Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,822 questions · 1,891 findings · 321 reviews · Headline outcomes only

No studies found 279 · 14.8%GRADE not reported 46 · 2.4%Very low 524 · 27.7%Low 571 · 30.2%Moderate 330 · 17.5%High 141 · 7.5%

Summary of findings: IMRT vs 3DCRT

Mean GI symptom scores (EORTC‐QLQPR25 scale; lower scores better) · People with urological (prostate) and gynaecological (cervical) cancer

Summary of findings: IMRT showed no clear difference in mean GI symptom scores (EORTC‐QLQPR25 scale; lower scores better) compared with 3DCRT (low certainty).

1 finding from 1 review

Intervention not reported

PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation

The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).

1 finding from 1 review

Intervention not reported

PIPP score during drug infusion Range of scale 0‐21 for infants < 28 weeks' PMA and 0‐18 for infants > 36 weeks' PMA. Lower score = less pain (Stevens 1996) · neonates requiring intubation and ventilation

The intervention showed no clear difference in PIPP score during drug infusion Range of scale 0‐21 for infants < 28… (moderate certainty).

1 finding from 1 review

Intervention not reported

New/intensified lipid‐lowering medication · adults without prevalent cardiovascular disease (primary cardiovascular disease prevention)

The intervention may leads to higher new/intensified lipid‐lowering medication (low certainty).

1 finding from 1 review

Intervention not reported

Activity limitations 100‐point Disabilities of the Arm, Shoulder and Hand questionnaire (lower score reflects better outcome) · people with non‐neurological conditions1
1 finding from 1 review

Intervention not reported

Pain 10‐point VAS (lower score reflects better outcome) · people with neurological conditions1
1 finding from 1 review

Intervention not reported

Pain 10‐point VAS (lower score reflects better outcome) · people with non‐neurological conditions1
1 finding from 1 review

Intervention not reported

Number of participants who experienced lower abdominal pain · Women undergoing excision of the cervical transformation zone for cervical neoplasia

The intervention showed no clear difference in number of participants who experienced lower abdominal pain (low certainty).

1 finding from 1 review