Intervention not reported
Mortality · antiretroviral‐naïve individuals
The intervention showed no clear difference in mortality (moderate certainty).
1 finding from 1 review
Intervention not reported
Progression to AIDS · antiretroviral‐naïve individuals
The intervention showed no clear difference in progression to AIDS (moderate certainty).
1 finding from 1 review
Intervention not reported
All severe adverse events · antiretroviral‐naïve individuals
It is very uncertain whether the intervention changes all severe adverse events (very low certainty).
1 finding from 1 review
Intervention not reported
Discontinuation rate · antiretroviral‐naïve individuals
The intervention showed no clear difference in discontinuation rate (moderate certainty).
1 finding from 1 review
Intervention not reported
Change in CD4 count · antiretroviral‐naïve individuals
1 finding from 1 review
Intervention not reported
Treatment failure · antiretroviral‐naïve individuals
The intervention showed no clear difference in treatment failure (low certainty).
1 finding from 1 review
Intervention not reported
Severe adverse events: central nervous system · antiretroviral‐naïve individuals
The intervention probably leads to higher severe adverse events: central nervous system (moderate certainty).
1 finding from 1 review
Intervention not reported
Severe adverse events: gastrointestinal · antiretroviral‐naïve individuals
The intervention showed no clear difference in severe adverse events: gastrointestinal (low certainty).
1 finding from 1 review
Intervention not reported
Overall survival · individuals with HL
1 finding from 1 review
Intervention not reported
PFS: relapse or death · individuals with HL
The intervention probably leads to higher PFS: relapse or death (moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events · individuals with HL
It is very uncertain whether the intervention changes adverse events (very low certainty).
1 finding from 1 review
Intervention not reported
Quality of life · individuals with HL
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Treatment related mortality · individuals with HL
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
CRC Mortality ‐ Flexible sigmoidoscopy · Asymptomatic individuals
The intervention leads to lower CRC Mortality ‐ Flexible sigmoidoscopy (high certainty).
1 finding from 1 review
Intervention not reported
CRC Mortality ‐ Faecal occult blood testing · Asymptomatic individuals
The intervention leads to lower CRC Mortality ‐ Faecal occult blood testing (high certainty).
1 finding from 1 review
Intervention not reported
CRC incidence ‐ Flexible sigmoidoscopy · Asymptomatic individuals
The intervention probably leads to lower CRC incidence ‐ Flexible sigmoidoscopy (moderate certainty).
1 finding from 1 review
Intervention not reported
CRC incidence ‐ Faecal occult blood testing · Asymptomatic individuals
The intervention leads to lower CRC incidence ‐ Faecal occult blood testing (high certainty).
1 finding from 1 review
Intervention not reported
All‐cause Mortality ‐ Flexible sigmoidoscopy · Asymptomatic individuals
The intervention showed no clear difference in all‐cause Mortality ‐ Flexible sigmoidoscopy (high certainty).
1 finding from 1 review
Intervention not reported
All‐cause Mortality ‐ Faecal occult blood testing · Asymptomatic individuals
The intervention leads to higher all‐cause Mortality ‐ Faecal occult blood testing (high certainty).
1 finding from 1 review
HIV infection · High‐risk HIV‐uninfected individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF+ FTC probably leads to lower HIV infection compared with placebo (moderate certainty).
1 finding from 1 review