Cochrane · systematic review · CD010533
Positron emission tomography‐adapted therapy for first‐line treatment in individuals with Hodgkin lymphoma
Sickinger, MT, von Tresckow, B, Kobe, C, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
HaematologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
3
No studies
2
Included studies
NR
No studies 2 · 40%Ungraded 0 · 0%Very low 2 · 40%Low 0 · 0%Moderate 1 · 20%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
PET‐adapted therapy in individuals with HL
Population: individuals with HL
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Overall survival | no estimate extracted | 3 studies · 1480 participants | Very low |
PFS: relapse or death | HR 2.38 [1.62, 3.5] | 3 studies · 1480 participants | Moderate |
Adverse events | RR 0.91 [0.54, 1.53] | 1 study · 160 participants | Very low Downgraded: imprecision, inconsistency, indirectness |
Quality of life | no estimate extracted | NR | No studies |
Treatment related mortality | no estimate extracted | NR | No studies |