Adverse event outcomes for dietary combined with physical activity interventions vs control
Body‐mass index z score (zBMI) · children aged 13‐18 years
1 finding from 1 review
- no estimate extracted6 studies · 16543 participantsLow
Findings
What do systematic reviews say?
1,100 questions · 1,164 findings · 107 reviews
No studies found 280 · 24.1%GRADE not reported 159 · 13.7%Very low 292 · 25.1%Low 274 · 23.5%Moderate 113 · 9.7%High 46 · 4%
Adverse event outcomes for dietary combined with physical activity interventions vs control
Body‐mass index (BMI) · children aged 13‐18 years
1 finding from 1 review
- no estimate extracted8 studies · 16583 participantsLow
Adverse event outcomes for dietary combined with physical activity interventions vs control
Body‐mass index z score (zBMI) · children aged 0‐5 years
1 finding from 1 review
- no estimate extracted16 studies · 6261 participantsModerate
Adverse event outcomes for dietary combined with physical activity interventions vs physical activity interventions
Body‐mass index (BMI) · children aged 6‐12 years
1 finding from 1 review
- no estimate extracted1 study · 3946 participantsHigh
Adverse event outcomes for dietary combined with physical activity interventions vs physical activity interventions
Body‐mass index z score (zBMI) · children aged 6‐12 years
1 finding from 1 review
- no estimate extracted1 study · 3946 participantsHigh
Adverse event outcomes for dietary combined with physical activity interventions vs control
Body‐mass index (BMI) · children aged 0‐5 years
1 finding from 1 review
- no estimate extracted11 studies · 5536 participantsModerate
Dietary supplements (alpha lipoic acid +/- vitamins) vs placebo
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- vitamins) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomeslong-term (>3 to 6 months)MD -0.89 [-2.37, 0.59]2 studies · 94 participantsVery low
Dietary supplements (hypericum perforatum / St John's Wort) vs placebo
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · hypericum perforatumHypericum perforatum extract (Sardella 2008, the only low-risk-of-bias study) contributes to the dietary supplements short-term symptom-relief comparison (insufficient/contradictory); no separate estimate reported.1 study · 43 participantsGRADE not reported
Dietary supplements (hypericum perforatum / St John's Wort) vs placebo
QoL · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · hypericum perforatumSardella 2008 (43 participants) evaluated QoL from patient self-reports and narratively indicated that both intervention and placebo participants were better able to cope at trial completion.1 study · 43 participantsGRADE not reported
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo
Adverse effects: intermittent facial skin rash · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: intermittent facial skin rash compared with placebo (very low certainty).
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)RR 8.71 [0.37, 205.80]1 study · 80 participantsVery low
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo
Gastrointestinal adverse events · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: gastrointestinal complaints compared with placebo (very low certainty).
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)RR 4.00 [1.21, 13.27]3 studies · 138 participantsVery low
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo
Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: drowsiness compared with placebo (very low certainty).
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)RR 1.00 [0.07, 14.85]1 study · 38 participantsVery low
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo
Adverse effects: headache · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: headache compared with placebo (very low certainty).
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)RR 10.87 [1.36, 87.03]2 studies · 118 participantsVery low
Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo
Adverse events: worsening of hypertension · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: increase in blood pressure compared with placebo (very low certainty).
1 finding from 1 review
- Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)RR 1.00 [0.07, 14.85]1 study · 38 participantsVery low
Adverse event outcomes for dietary combined with physical activity interventions vs control
Accidents · children aged 0 to 5 years
1 finding from 1 review
- no estimate extracted1 study · 42 participantsVery low
Adverse event outcomes for dietary combined with physical activity interventions vs usual care or no treatment
Underweight · children aged 6 to 12 years
2 findings from 1 review
- no estimate extracted2 studies · 784 participantsModerate
- no estimate extracted1 study · 724 participantsModerate
Adverse event outcomes for dietary combined with physical activity interventions vs usual care or no treatment
Depression · children aged 6 to 12 years
1 finding from 1 review
- no estimate extracted1 study · 225 participantsLow
Adverse event outcomes for dietary combined with physical activity interventions vs usual care or no treatment
Increased weight concern · children aged 6 to 12 years
1 finding from 1 review
- no estimate extracted2 studies · 285 participantsHigh
Adverse event outcomes for dietary combined with physical activity interventions vs usual care or no treatment
Body satisfaction · children aged 6 to 12 years
1 finding from 1 review
- no estimate extracted3 studies · 1128 participantsHigh
Adverse event outcomes for dietary combined with physical activity interventions vs usual care or no treatment
Visits to a healthcare provider · children aged 6 to 12 years
1 finding from 1 review
- no estimate extracted1 study · 60 participantsLow