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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Vapour‐permeable dressings · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 1.45 [0.74, 2.81]NRVery low
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Alginate dressings · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 1.09 [0.11, 10.57]NRVery low
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Sequential hydrocolloid alginate dressings · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 0.5 [0.12, 1.98]NRVery low
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Basic wound contact dressings · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 1.3 [0.65, 2.58]NRLow
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Collagenase ointment · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 2.12 [1.06, 4.22]NRLow
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Dextranomer · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 4.76 [0.86, 26.39]NRVery low
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Foam dressings · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 1.52 [1.03, 2.26]NRLow
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Hydrocolloid dressing with/without alginate · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 1.22 [0.06, 24.74]NRVery low
NMA evidence for individual network: proportion with complete healing ‐ interventions vs saline gauze
Hydrocolloid dressings · people with pressure ulcers
Dressings and topical agents for treating pressure ulcers (2017) · Cochrane
RR 1.43 [1, 2.05]NRVery low
Phototherapy vs placebo/no phototherapy
Wound healing ‐ time to complete wound healing (weeks) · Diabetes with foot ulcers
Phototherapy for treating foot ulcers in people with diabetes (2017) · Cochrane
no estimate extractedNRNo studies
Phototherapy vs placebo/no phototherapy
Wound healing ‐ proportion of wounds completely healed during · Diabetes with foot ulcers
Phototherapy for treating foot ulcers in people with diabetes (2017) · Cochrane
RR 1.57 [1.08, 2.28]4 studies · 116 participantsLow
Phototherapy vs placebo/no phototherapy
Adverse events · Diabetes with foot ulcers
Phototherapy for treating foot ulcers in people with diabetes (2017) · Cochrane
no estimate extractedNRNo studies
All irrigation vs no irrigation
SSI · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 0.87 [0.68, 1.11]14 studies · 6106 participantsLow
Standard irrigation vs pulsatile irrigation
Wound dehiscence · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 0.31 [0.01, 7.55]1 study · 128 participantsLow
Standard irrigation vs pulsatile irrigation
Adverse events · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 1.31 [0.87, 1.97]1 study · 128 participantsLow
Standard irrigation vs pulsatile irrigation
Adverse events: abscess formation · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
no estimate extractedNRNo studies
All irrigation vs no irrigation
Wound dehiscence · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 1.17 [0.44, 3.06]1 study · 30 participantsLow
All irrigation vs no irrigation
Adverse events · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 1.05 [0.76, 1.44]3 studies · 403 participantsLow
All irrigation vs no irrigation
Adverse events: abscess formation · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 0.91 [0.54, 1.54]3 studies · 331 participantsModerate
Irrigation with antibacterial solution vs irrigation with non‐antibacterial solution
SSI · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 0.57 [0.44, 0.75]30 studies · 5141 participantsLow
Irrigation with antibacterial solution vs irrigation with non‐antibacterial solution
Wound dehiscence · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 1.26 [0.65, 2.45]3 studies · 660 participantsVery low
Irrigation with antibacterial solution vs irrigation with non‐antibacterial solution
Adverse events · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 0.55 [0.22, 1.34]3 studies · 178 participantsLow
Irrigation with antibacterial solution vs irrigation with non‐antibacterial solution
Adverse events: abscess formation · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 0.82 [0.42, 1.62]9 studies · 1309 participantsVery low
Standard irrigation vs pulsatile irrigation
SSI · participants undergoing clean, clean‐contaminated, contaminated or dirty surgical procedures
Intracavity lavage and wound irrigation for prevention of surgical site infection (2017) · Cochrane
RR 0.34 [0.19, 0.62]2 studies · 484 participantsLow
Mupirocin vs placebo
SSI · S aureus carriers undergoing cardiac surgery
Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers (2017) · Cochrane
RR 1.6 [0.79, 3.25]1 study · 257 participantsLow
Mupirocin vs placebo
S aureus SSI · S aureus carriers undergoing cardiac surgery
Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers (2017) · Cochrane
RR 1.22 [0.34, 4.44]1 study · 257 participantsLow
Mupirocin vs placebo
Mortality · S aureus carriers undergoing cardiac surgery
Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers (2017) · Cochrane
RR 0.78 [0.21, 2.84]1 study · 257 participantsLow
Mupirocin vs placebo
Adverse events · S aureus carriers undergoing cardiac surgery
Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers (2017) · Cochrane
no estimate extracted1 study · 257 participantsUngraded
Anerdian vs no treatment
SSI · S aureus carriers undergoing cardiac surgery
Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers (2017) · Cochrane
RR 0.89 [0.06, 13.08]1 study · 34 participantsVery low
Anerdian vs no treatment
Adverse events · S aureus carriers undergoing cardiac surgery
Nasal decontamination for the prevention of surgical site infection in Staphylococcus aureus carriers (2017) · Cochrane
no estimate extracted1 study · 34 participantsUngraded
Basic wound contact dressing vs exposed wound
SSI Assessment method: clinical features of infection · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Silver dressing vs exposed wound
Scarring · surgical wounds resulting from surgery at risk of contamination and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Silver dressing vs exposed wound
Acceptability · surgical wounds resulting from surgery at risk of contamination and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Silver dressing vs exposed wound
Ease of dressing removal · surgical wounds resulting from surgery at risk of contamination and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
SSI Assessment method: various methods · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
Scarring · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
Acceptability of dressing to participant Clean surgery Assessment method:VAS, participants rated dressing acceptability (0 = no trouble and 10 = very troublesome) · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs film dressing
Ease of dressing removal Assessment method: unclear · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
SSIClean surgery Assessment method: CDC definition of SSI · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
Scarring Clean surgery Assessment method: participants assessed different aspects of scarring as either: excellent, good or fair · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
Acceptability of dressing to participant Clean surgery Assessment method: participants rated whether they were dissatisfied with the dressing · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs exposed wound
Scarring (further information not reported) · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs hydrocolloid dressing
Ease of dressing removal Clean surgery Assessment method: questions regarding dressing removal · surgical wounds healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs fibrous‐hydrocolloid dressing
SSI Assessment method: signs of infection (redness, tenderness, swelling or exudate) · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
RR 1.29 [0.5, 3.28]3 studies · 364 participantsVery low
Basic wound contact dressing vs fibrous‐hydrocolloid dressing
Scarring · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extracted1 study · 80 participantsUngraded
Basic wound contact dressing vs fibrous‐hydrocolloid dressing
Acceptability of dressing to participant · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs fibrous‐hydrocolloid dressing
Ease of dressing removal · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs polyurethane matrix hydrocolloid dressings
SSI · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs polyurethane matrix hydrocolloid dressings
Scarring · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies
Basic wound contact dressing vs polyurethane matrix hydrocolloid dressings
Acceptability of dressing to participant · surgical wounds resulting from clean surgery and healing by primary intention
Dressings for the prevention of surgical site infection (2016) · Cochrane
no estimate extractedNRNo studies