Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,234 questions · 3,357 findings · 396 reviews

No studies found 803 · 23.9%GRADE not reported 270 · 8%Very low 757 · 22.5%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Hinokitiol gel vs Placebo gel

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 4 weeks
    Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
    0 studies
    No studies found

Hinokitiol gel vs Placebo gel

VSC: methyl mercaptan · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Hinokitiol gel showed no clear difference in VSC: methyl mercaptan compared with placebo gel; GRADE not reported.

1 finding from 1 review

Hinokitiol gel vs Placebo gel

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether hinokitiol gel changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with placebo gel (very low certainty).

1 finding from 1 review

Hinokitiol gel vs Placebo gel

Patient-reported OLT score · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 4 weeks
    Patient-reported OLT score: listed in the Summary of findings table but no data reported. No data were reported for patient-reported OLT score.
    0 studies
    No studies found

Hinokitiol gel vs Placebo gel

VSC: hydrogen sulphide · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Hinokitiol gel showed no clear difference in VSC: hydrogen sulphide compared with placebo gel; GRADE not reported.

1 finding from 1 review

Fluoroquinolones vs amoxicillin

Response rate ‐ treatment failure · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis

Fluoroquinolones may leads to lower response rate ‐ treatment failure compared with amoxicillin (low certainty).

1 finding from 1 review

Fluoroquinolones vs amoxicillin

Response rate ‐ microbiological response · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis

Fluoroquinolones may leads to higher response rate ‐ microbiological response compared with amoxicillin (low certainty).

1 finding from 1 review

Fluoroquinolones vs amoxicillin

Response rate ‐ improvement in sputum purulence (excellent) · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis

It is very uncertain whether fluoroquinolones changes response rate ‐ improvement in sputum purulence (excellent) compared with amoxicillin (very low certainty).

1 finding from 1 review

Fluoroquinolones vs beta‐lactams

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes other adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review