Chemotherapy + ART vs chemotherapy alone
It is very uncertain whether chemotherapy + ART changes complete Among Known Outcome compared with chemotherapy Alone (very low certainty).
- RR 4.25 [0.7, 25.91]30 participantsVery low
It is very uncertain whether chemotherapy + ART changes complete Among Known Outcome compared with chemotherapy Alone (very low certainty).
It is very uncertain whether chemotherapy + ART changes complete/Partial Among Known Outcome compared with chemotherapy Alone (very low certainty).
It is very uncertain whether chemotherapy + ART changes mortality compared with chemotherapy Alone (very low certainty).
The intervention may leads to higher objective response rate2 (low certainty).
It is very uncertain whether artesunate (12 mg/kg) plus praziquantel (40 mg/kg) changes parasitological failure at 1 month compared with praziquantel (40 mg/kg) alone (very low certainty).
Aripiprazole leads to higher requirement for anticholinergics number of participants requiring… compared with placebo (high certainty).
Any Psychosocial intervention plus pharm showed no clear difference in retention in treatment Objective compared with pharm standard (high certainty).
Any Psychosocial intervention plus pharm showed no clear difference in opioid abstinence objective compared with pharm standard (high certainty).
NBI + WLC TURBT may leads to lower time to disease recurrence compared with WLC TURBT (low certainty).
The review found no eligible studies for this question.
NBI + WLC TURBT showed no clear difference in major adverse event (Clavien‐Dindo grade III, IV, and V) compared with WLC TURBT (low certainty).
The review found no eligible studies for this question.
NBI + WLC TURBT showed no clear difference in minor adverse event (Clavien‐Dindo grade I and II) compared with WLC TURBT (low certainty).
IRI with fluoropyrimidines showed no clear difference in overall survival (Death) compared with single agent IRI (low certainty).
IRI with fluoropyrimidines probably leads to lower progression‐free survival (Disease progression) compared with single agent IRI (moderate certainty).
IRI with fluoropyrimidines probably leads to lower grade 3/4 diarrhea compared with single agent IRI (moderate certainty).
IRI with fluoropyrimidines showed no clear difference in grade 3/4 nausea compared with single agent IRI (low certainty).
The intervention probably leads to lower lymph node mets analysis ‐ N+ OS (moderate certainty).
The intervention probably leads to lower chemobased OS ‐ 5‐FU based chemotherapy OS (moderate certainty).