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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,361 questions in 120 reviews · Developmental, Psychosocial and Learning Problems

current versions
No studies 286 · 21%Ungraded 61 · 4.5%Very low 381 · 28%Low 381 · 28%Moderate 228 · 16.8%High 24 · 1.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings: Specially formulated foods vs Standard care
Recovered · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 1.29 [1.2, 1.38]2 studies · 2152 participantsModerate
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
Progression to SAM · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 0.88 [0.72, 1.07]3 studies · 4537 participantsHigh
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
Died · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 0.93 [0.54, 1.62]5 studies · 6367 participantsModerate
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
Defaulted · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 1.14 [0.62, 2.11]4 studies · 5107 participantsModerate
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
Weight gain, daily · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted3 studies · 3223 participantsModerate
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
WHZ gain · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted2 studies · 3631 participantsModerate
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
MUAC gain · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted3 studies · 3550 participantsModerate
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
Vomiting · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 1.43 [1.11, 1.85]1 study · 2712 participantsLow
Summary of findings: Lipid‐based nutrient supplements vs CSB++
Recovered · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 1.04 [0.99, 1.09]3 studies · 4758 participantsModerate
Summary of findings: Lipid‐based nutrient supplements vs CSB++
Progression to SAM · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 0.84 [0.69, 1.02]2 studies · 4081 participantsHigh
Summary of findings: Lipid‐based nutrient supplements vs CSB++
Defaulted · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 1.27 [0.75, 2.16]2 studies · 4081 participantsHigh
Summary of findings: Specially formulated foods vs Standard care
Not recovered · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 0.97 [0.74, 1.27]1 study · 1974 participantsLow
Summary of findings: Lipid‐based nutrient supplements vs CSB++
Weight gain · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted2 studies · 3389 participantsModerate
Summary of findings: Lipid‐based nutrient supplements vs CSB++
WHZ gain · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted3 studies · 3048 participantsModerate
Summary of findings: Lipid‐based nutrient supplements vs CSB++
MUAC gain · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted2 studies · 3730 participantsModerate
Summary of findings: Lipid‐based nutrient supplements vs CSB++
Height gain · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted2 studies · 3730 participantsHigh
Summary of findings: Specially formulated foods vs Standard care
Defaulted · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 0.3 [0.22, 0.39]1 study · 1974 participantsModerate
Summary of findings: Specially formulated foods vs Standard care
Weight gain, total · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted1 study · 178 participantsLow
Summary of findings: Specially formulated foods vs Standard care
WHZ final · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted2 studies · 1546 participantsModerate
Summary of findings: Specially formulated foods vs Standard care
MUAC gain · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted1 study · 178 participantsVery low
Summary of findings: Specially formulated foods vs Standard care
HAZ final · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
no estimate extracted2 studies · 1546 participantsLow
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
Recovered · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 1.1 [1.04, 1.16]5 studies · 6367 participantsModerate
Summary of findings: Lipid‐based nutrient supplements (full dose) vs Blended foods (full dose)
Not recovered · children with MAM
Specially formulated foods for treating children with moderate acute malnutrition in low‐ and middle‐income… (2013) · Cochrane
RR 0.53 [0.4, 0.69]3 studies · 4537 participantsHigh
Intervention NR
Language ‐ joint (direct or independent assessment) EIDP/PSDP, PLS‐IV/CASL1 · children aged 1 year to 6 years 11 months with diagnosis of ASD
Parent‐mediated early intervention for young children with autism spectrum disorders (ASD) (2013) · Cochrane
no estimate extracted2 studies · 64 participantsLow
Intervention NR
Communication (reported) VABS1 · children aged 1 year to 6 years 11 months with diagnosis of ASD
Parent‐mediated early intervention for young children with autism spectrum disorders (ASD) (2013) · Cochrane
no estimate extracted3 studies · 228 participantsLow
Intervention NR
Language – expression (direct or independent assessment) PLS‐IV, MSEL1 · children aged 1 year to 6 years 11 months with diagnosis of ASD
Parent‐mediated early intervention for young children with autism spectrum disorders (ASD) (2013) · Cochrane
no estimate extracted3 studies · 264 participantsLow
Intervention NR
Language – Comprehension (direct or independent assessment) PLS, MSEL1 · children aged 1 year to 6 years 11 months with diagnosis of ASD
Parent‐mediated early intervention for young children with autism spectrum disorders (ASD) (2013) · Cochrane
no estimate extracted2 studies · 200 participantsLow
Intervention NR
Parent‐child interaction (parent synchrony) · children aged 1 year to 6 years 11 months with diagnosis of ASD
Parent‐mediated early intervention for young children with autism spectrum disorders (ASD) (2013) · Cochrane
no estimate extracted3 studies · 244 participantsLow
Intervention NR
Parents'level of stress PSI, SAC1 · children aged 1 year to 6 years 11 months with diagnosis of ASD
Parent‐mediated early intervention for young children with autism spectrum disorders (ASD) (2013) · Cochrane
no estimate extracted2 studies · 55 participantsLow
Manipulative therapy vs control condition
Change in daily hours of crying Crying diary completed by parents · infants with colic
Manipulative therapies for infantile colic (2012) · Cochrane
no estimate extracted5 studies · 223 participantsLow
Manipulative therapy vs control condition
Presence/absence of colic Global impression of change scale completed by parents · infants with colic
Manipulative therapies for infantile colic (2012) · Cochrane
OR 11.12 [0.46, 267.52]3 studies · 185 participantsLow
Manipulative therapy vs control condition
Adverse events Incidents reported by parents · infants with colic
Manipulative therapies for infantile colic (2012) · Cochrane
no estimate extracted1 study · 102 participantsUngraded
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Weight (kg) at the end of the intervention Weight scale · Children aged less than 24 months
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 460 participantsLow
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Weight (kg) at the end of the intervention Weight scale · Children aged less than five years with or without stunting or wasting
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 460 participantsLow
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Length/height (cm) at the end of the intervention Measurement board · Children aged less than five years with or without stunting or wasting
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 460 participantsLow
Supplementary feeding vs no food supplementation or placebo
Weight‐for‐length/height z‐score at the end of the intervention Weight scale and measurement board · Children aged less than five years with or without stunting/wasting in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 260 participantsModerate
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Weight (kg) at the end of the intervention Weight scale · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 587 participantsLow
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Length/height (cm) at the end of the intervention Measurement board · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 587 participantsLow
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Weight gain (kg) during the intervention Weight scale · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted2 studies · 795 participantsVery low
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Length/height gain (cm) at the end of the intervention Measurement board · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted2 studies · 795 participantsVery low
Supplementary feeding vs no food supplementation or placebo
Weight‐for‐age z‐score at the end of the intervention Weight scale and child growth reference · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 308 participantsModerate
Supplementary feeding vs no food supplementation or placebo
Length/height‐for‐age z‐score at the end of the intervention Measurement board and child growth reference · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 308 participantsLow
Supplementary feeding vs no food supplementation or placebo
Weight‐for‐length/height z‐score at the end of the intervention Weight scale, measurement boards and child growth reference · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 260 participantsModerate
Supplementary feeding vs no food supplementation or low‐protein/kcalories supplementation
Lenght/height (cm) at the end of the intervention Measurement board · Children aged less than 24 months
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 460 participantsLow
Supplementary feeding vs no food supplementation
Change in weight‐for‐age z‐core during the intervention Weight scale and and child growth reference · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted1 study · 348 participantsLow
Supplementary feeding vs no food supplementation
Change in length/height z‐score during the intervention Measurement board and child growth reference · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted1 study · 348 participantsLow
Supplementary feeding vs no food supplementation or placebo
Weight gain (kg) during the intervention Weight scale · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted2 studies · 668 participantsVery low
Supplementary feeding vs no food supplementation or placebo
Length/height gain (cm) at the end of the intervention Measurement board · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted2 studies · 795 participantsVery low
Supplementary feeding vs no food supplementation or placebo
Weight‐for‐age z‐score at the end of the intervention Weight scale and child growth reference · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 308 participantsModerate
Supplementary feeding vs no food supplementation or placebo
Lenght/height‐for‐age z‐score at the end of the intervention Measurement board and child growth reference · Children aged less than five years in LMIC
Community‐based supplementary feeding for promoting the growth of children under five years of age in low… (2012) · Cochrane
no estimate extracted3 studies · 308 participantsLow