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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

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No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only

50% or greater reduction in seizure frequency · people with ADHD and epilepsy

Omega‐3 (with risperidone and previous ASM) showed no clear difference in proportion of people achieving 50% or greater reduction in monthly… compared with risperidone and previous ASM only (low certainty).

1 finding from 1 review

Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only

Adverse drug events · people with ADHD and epilepsy

Omega‐3 (with risperidone and previous ASM) showed no clear difference in proportion of people experiencing adverse drug events compared with risperidone and previous ASM only (low certainty).

1 finding from 1 review

Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only

Proportion of individuals withdrawing from treatment · people with ADHD and epilepsy

Omega‐3 (with risperidone and previous ASM) showed no clear difference in proportion of individuals withdrawing from treatment compared with risperidone and previous ASM only (low certainty).

1 finding from 1 review

Summary of findings: endovenous ablation and compression vs compression alone

Ulcer healing time (measured as days from randomisation and followed‐up to 1 year) · people with venous leg ulcers

Summary of findings: endovenous ablation and compression leads to higher ulcer healing time (measured as days from randomisation and… compared with compression alone (high certainty).

1 finding from 1 review

Summary of findings: endovenous ablation and compression vs compression alone

The proportion of pressure ulcers healed · people with venous leg ulcers

Summary of findings: endovenous ablation and compression showed no clear difference in proportion of ulcers healed at 90 days (90 days compared with compression alone (moderate certainty).

2 findings from 1 review