Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

625 questions · 647 findings · 67 reviews · Pregnancy and Childbirth

No studies found 83 · 12.8%GRADE not reported 70 · 10.8%Very low 141 · 21.8%Low 227 · 35.1%Moderate 97 · 15%High 29 · 4.5%

Beta stimulant vs placebo

Cephalic vaginal birth not achieved (CS + breech vaginal birth) (primary) · patients with breech presentation

Beta stimulant probably leads to lower cephalic vaginal birth not achieved (CS + breech vaginal birth)… compared with placebo (moderate certainty).

1 finding from 1 review

Rutosides vs placebo

Complications associated with varicose veins and leg oedema (deep vein thrombosis) · Pregnant women with varicose veins and leg oedema in pregnancy

Rutoside showed no clear difference in complications associated with varicose veins and leg oedema (deep… compared with placebo (moderate certainty).

1 finding from 1 review

Rutosides vs placebo

Symptoms associated with varicose veins and oedema (improvement in symptoms) · Pregnant women with varicose veins and leg oedema in pregnancy

Rutoside probably leads to higher symptoms associated with varicose veins and oedema (improvement in… compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic antibiotics vs placebo

Preterm prelabour rupture of membranes · women in the second or third trimester of pregnancy before labour and delivery

Prophylactic antibiotics showed no clear difference in preterm prelabour rupture of membranes compared with placebo (low certainty).

1 finding from 1 review