Cochrane · systematic review · CD012048

Dietary supplementation with myo‐inositol in women during pregnancy for treating gestational diabetes

Brown, J, Crawford, TJ, Alsweiler, J, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 12 · 85.7%Very low 0 · 0%Low 2 · 14.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Myo‐inositol versus placebo for the treatment of gestational diabetes ‐ Neonatal outcomes

Population: pregnant women with gestational diabetes
7 questions
OutcomeEffectEvidenceStatus / GRADE
Large‐for‐gestational age
Myo‐inositol vs placebo
RR 0.36 [0.02, 8.58]1 study · 73 participantsLow
Downgraded: imprecision
Perinatal mortality
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Neonatal hypoglycaemia
Myo‐inositol vs placebo
RR 0.05 [0, 0.85]1 study · 73 participantsLow
Downgraded: imprecision
Composite outcome of serious neonatal outcomes
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Childhood/adulthood adiposity
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Childhood/adulthood diabetes
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Neurosensory disability
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded

Myo‐inositol versus placebo for the treatment of gestational diabetes ‐ Maternal outcomes

Population: pregnant women with gestational diabetes
7 questions
OutcomeEffectEvidenceStatus / GRADE
Hypertensive disorders of pregnancy
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Caesarean section
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Induction of labour
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Perineal trauma
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Postnatal weight retention/return to pre‐pregnancy weight
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Postnatal depression
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded
Development of subsequent type 2 diabetes mellitus
Myo‐inositol vs placebo
no estimate extracted0 studies · 0 participantsUngraded