Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

603 questions · 627 findings · 69 reviews · Pain, Palliative and Supportive Care

No studies found 111 · 17.7%GRADE not reported 27 · 4.3%Very low 191 · 30.5%Low 138 · 22%Moderate 100 · 15.9%High 60 · 9.6%

Oxycodone MR vs placebo

'Substantial benefit' (≥ 50% reduction in pain or PGIC very much improved) · adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)
1 finding from 1 review

Oxycodone MR vs placebo

Moderate benefit: At least 30% reduction in pain, or PGIC much or very much improved · adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)
1 finding from 1 review

Oxycodone MR vs placebo

Withdrawals due to adverse events · adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)
1 finding from 1 review

Oxycodone MR vs placebo

Lack of efficacy withdrawal · adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)
1 finding from 1 review

Oxycodone MR vs placebo

Serious adverse events · adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)
1 finding from 1 review

Oral hydromorphone vs placebo

Moderate benefit: At least 30% reduction in pain, or PGIC much or very much improved · adults with chronic neuropathic pain

The review found no eligible studies for this question.

1 finding from 1 review