PUFA vs monounsaturated fatty acid (MUFA)
- Dietary interventions for multiple sclerosis‐related outcomes 2020 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 102 participantsVery low
Polyunsaturated fatty acid (PUFA) showed no clear difference in global impression of deterioration (investigator defined global… compared with monounsaturated fatty acid (MUFA) (low certainty).
The review found no eligible studies for this question.
Omega‐3 showed no clear difference in relapse(assessed as number of participants experiencing relapse) compared with omega‐6 (low certainty).
Omega‐3 showed no clear difference in global impression of deterioration (investigator defined global… compared with omega‐6 (moderate certainty).
The intervention showed no clear difference in proportion of participants who experienced operative or… (moderate certainty).
The intervention showed no clear difference in proportion of participants who experienced improvement of composite… (moderate certainty).
The intervention showed no clear difference in proportion of participants who experienced new relapses over 12 months (moderate certainty).
Intramuscular (IM) progesterone showed no clear difference in perinatal death compared with no treatment or placebo (low certainty).
Vaginal progesterone showed no clear difference in infant birthweight less than 2500 g compared with no treatment or placebo (moderate certainty).
Vaginal progesterone showed no clear difference in preterm birth less than 37 weeks compared with no treatment or placebo (moderate certainty).
Vaginal progesterone showed no clear difference in preterm birth less than 28 weeks compared with no treatment or placebo (low certainty).
Intramuscular (IM) progesterone may leads to higher preterm birth less than 34 weeks compared with no treatment or placebo (low certainty).
Intramuscular (IM) progesterone showed no clear difference in infant birthweight less than 2500 g compared with no treatment or placebo (moderate certainty).
Intramuscular (IM) progesterone showed no clear difference in preterm birth less than 28 weeks compared with no treatment or placebo (moderate certainty).
Intramuscular (IM) progesterone showed no clear difference in preterm birth less than 37 weeks compared with no treatment or placebo (high certainty).