Cochrane · systematic review · CD009903
Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency (CCSVI) in people with multiple sclerosis
Jagannath, VA, Pucci, E, Asokan, GV, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Multiple Sclerosis and Rare Diseases of the CNSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: patients with multiple sclerosis and chronic cerebrospinal venous insufficiency (CCSVI)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of participants who experienced operative or postoperative serious adverse events | RR 3.33 [0.36, 30.44] | 3 studies · 238 participants | Moderate |
Proportion of participants who experienced improvement of composite functional endpoint over 12 months | RR 0.84 [0.55, 1.3] | 1 study · 110 participants | Moderate |
Proportion of participants who experienced new relapses over 12 months | RR 0.87 [0.51, 1.49] | 3 studies · 235 participants | Moderate |