Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Service utilisation ‐ unplanned hospitalisations (1 to 6 months post intervention) (RR < 1 denotes lower risk) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether lay health worker‐led interventions for adult patients with harmful… changes service utilisation ‐ unplanned hospitalisations (1 to 6 months post… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether lay health worker‐led interventions for adult patients with harmful… changes adverse events ‐ deaths (RR < 1 denotes lower risk) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Cannabis use · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether primary health professional‐ and community professional‐led… changes prevalence of cannabis use (1 to 6 months post intervention) (RR < 1… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Adverse events RR < 1 indicates lower risk of adverse events · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower adverse events RR < 1 indicates lower risk of adverse events compared with usual care (low certainty).

1 finding from 1 review

Primary‐level worker‐led collaborative care vs usual care

Prevalence of CMD ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by presence of ICD‐10 diagnosis on CIS‐Rg; prevalence defined by [Total number ‐ number recovered (recovery defined by HDRS < 8)]c (RR < 1 denotes lower prev... · adults with common mental disorders

Primary‐level worker‐led collaborative care showed no clear difference in prevalence of CMD ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Active exercise regimen vs an immobilisation regimen following surgery

Range of movement · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

It is very uncertain whether active exercise regimen changes range of movement compared with an immobilisation regimen following surgery (very low certainty).

2 findings from 1 review

Active exercise regimen vs an immobilisation regimen following surgery

Adverse events requiring (or indicated for) surgery · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

It is very uncertain whether active exercise regimen changes adverse events requiring (or indicated for) surgery compared with an immobilisation regimen following surgery (very low certainty).

1 finding from 1 review

Place and hold exercise regimen vs controlled passive exercise regimen following surgery

Functional assessment using a patient reported outcome measure: · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa
2 findings from 1 review

Place and hold exercise regimen vs controlled passive exercise regimen following surgery

Range of movement · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

The review found no eligible studies for this question.

2 findings from 1 review

Place and hold exercise regimen vs controlled passive exercise regimen following surgery

Adverse events requiring (or indicated for) surgery · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

It is very uncertain whether place and hold exercise regimen changes adverse events requiring (or indicated for) surgery compared with controlled passive exercise regimen following surgery (very low certainty).

1 finding from 1 review

Active exercise regimen vs an immobilisation regimen following surgery

Functional assessment using a patient reported outcome measure: · participants undergoing rehabilitation following surgery for flexor tendon injuries of the handa

The review found no eligible studies for this question.

2 findings from 1 review