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Evidence found and GRADE certainty

778 questions · 809 findings · 116 reviews

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No studies found 205 · 25.3%GRADE not reported 111 · 13.7%Very low 225 · 27.8%Low 155 · 19.2%Moderate 85 · 10.5%High 28 · 3.5%

Oral-health promotion programs (OHPPs): community-based oral-health education/training, supervised toothbrushing with fluoride toothpaste and topical fluoride, dental screening, and dietary advice vs No oral-health promotion program, or a differing (usual-care) action under similar conditions

DMFT/DMFS index (dental caries experience) · Children aged 0-12 years (studies published 2015 or later)

In studies published from 2015 onward, OHPPs were associated with lower DMFT (OR 0.08, 95% CI 0.01 to 0.53; ungraded).

1 finding from 1 review

Conventional occlusion vs atropine penalization

Visual acuity · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…
2 findings from 1 review

Conventional occlusion vs atropine penalization

Ocular alignment (different measures and time points reported in the included studies) Assessed at different time points (17 weeks, 24 months, or cessation of treatment) and by the proportions of participants who developed strabismus, showed chang... · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…
1 finding from 1 review

Conventional occlusion vs atropine penalization

Stereo acuity (different measures and time points reported in the included studies) Assessed at different time points (17 weeks, 6 months, 2 years, or at cessation of treatment) and using different measures (TNO stereo test, Titmus fly test, Rando... · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…
1 finding from 1 review

Conventional occlusion vs atropine penalization

Quality of life (different measures and time points reported in the included studies) Assessed at different time points (17 weeks or 6 months) by patient preference or the Amblyopia Treatment Index questionnaire. · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…
1 finding from 1 review

Conventional occlusion vs atropine penalization

Adverse events (reported occurrence of: mild reduction in the visual acuity of the sound eye not requiring treatment; light sensitivity; skin, lid, or conjunctival irritation) Assessed at different time points (17 weeks or 2 years). · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…
1 finding from 1 review

Active vs expectant management of the third stage of labour (all women)

Severe PPH (≥ 1000 mL) · all women who expected a vaginal birth at 24 weeks' gestation or later and their babies

It is very uncertain whether active changes severe primary PPH (clinically estimated or measured blood loss ≥… compared with expectant management of the third stage of labour (all women) (very low certainty).

1 finding from 1 review