All psychological therapies showed no clear difference in short‐term response compared with tricyclic antidepressants (low certainty).
All psychological therapies showed no clear difference in dropouts for any reason compared with tricyclic antidepressants (low certainty).
Comparison 4: Adherence enhancement approaches showed no clear difference in repetition of SH at 12 months' compared with treatment (low certainty).
Comparison 1: CBT‐based psychotherapy probably leads to lower repetition of SH at 6 months compared with treatment (moderate certainty).
Comparison 1: CBT‐based psychotherapy probably leads to lower repetition of SH at 12 months compared with treatment (moderate certainty).
Comparison 1: CBT‐based psychotherapy probably leads to lower repetition of SH at 24 months compared with treatment (moderate certainty).
Comparison 1: CBT‐based psychotherapy may leads to lower repetition of SH at final compared with treatment (low certainty).
Newer generation antidepressants showed no clear difference in repetition of SH at last compared with placebo (low certainty).
It is very uncertain whether antipsychotics changes repetition of SH at six months (flupenthixol vs. placebo) compared with placebo or another comparator drug/dose (very low certainty).
It is very uncertain whether antipsychotics changes repetition of SH at six months (low dose fluphenazine vs. ultra low… compared with placebo or another comparator drug/dose (very low certainty).
Mood stabilisers showed no clear difference in repetition of SH at 12 months compared with placebo (low certainty).
Natural products showed no clear difference in repetition of SH during 12 week treatment phase compared with placebo (low certainty).
It is very uncertain whether comparison 1: individual CBT‐based psychotherapy changes repetition of SH at six months compared with treatment (very low certainty).
Comparison 5: group‐based psychotherapy showed no clear difference in repetition of SH at six months compared with treatment (low certainty).
Comparison 5: group‐based psychotherapy showed no clear difference in repetition of SH at 12 months compared with treatment (low certainty).
Comparison 6: therapeutic assessment showed no clear difference in repetition of SH at 12 months compared with treatment (low certainty).
Comparison 6: therapeutic assessment showed no clear difference in repetition of SH at 24 months compared with treatment (low certainty).
It is very uncertain whether comparison 7: compliance enhancement plus treatment as usual (i.e.,… changes repetition of SH by six months compared with treatment (very low certainty).