Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,888 questions · 2,009 findings · 352 reviews

No studies found 224 · 11.1%GRADE not reported 265 · 13.2%Very low 551 · 27.4%Low 540 · 26.9%Moderate 311 · 15.5%High 118 · 5.9%

Summary of findings table ‐ Progestogens vs GnRH antagonists

Oocyte pick‐up cancellation · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in oocyte pick‐up cancellation ‐ Normoresponders (MPA 10 mg versus GnRH… compared with gnRH antagonists; GRADE not reported.

2 findings from 1 review

Cephalomedullary nails vs extramedullary implants

Functional status, early (within 4 months): using HHS (range from 0 to 100) and Johansen hip score (range from 0 to 100); higher scores indicate better function · older adults (> 60 years of age) with extracapsular hip fractures

Cephalomedullary nails showed no clear difference in functional status, early (≤ 4 months): using Zűckerman functional… compared with extramedullary implants (low certainty).

1 finding from 1 review

Cephalomedullary nails vs extramedullary implants

Mortality, early (≤ 4 months) · older adults (> 60 years of age) with extracapsular hip fractures

Cephalomedullary nails showed no clear difference in mortality, early (≤ 4 months) compared with extramedullary implants (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C1: Total deaths (after randomisation) up to early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C1: Total deaths (after randomisation) up to early childhood compared with single course (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C2: Neurodevelopmental impairment at early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C2: Neurodevelopmental impairment at early childhood compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C3: Survival free of neurodevelopmental impairment at early childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C3: Survival free of neurodevelopmental impairment at early childhood compared with single course (high certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

C4: Survival free of major neurodevelopmental impairment atearly childhood · the child

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in C4: Survival free of major neurodevelopmental impairment atearly… compared with single course (moderate certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs IPC alone

Incidence of PEa (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

IPC plus pharmacological prophylaxis may leads to lower incidence of PEa (early postoperative period) compared with IPC alone (low certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs IPC alone

Incidence of DVTc (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

IPC plus pharmacological prophylaxis may leads to lower incidence of DVTc (early postoperative period) compared with IPC alone (low certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs IPC alone

Incidence of bleedingd (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

It is very uncertain whether IPC plus pharmacological prophylaxis changes incidence of bleedingd (early postoperative period) compared with IPC alone (very low certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs IPC alone

Incidence of major bleedingf (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

It is very uncertain whether IPC plus pharmacological prophylaxis changes incidence of major bleedingf (early postoperative period) compared with IPC alone (very low certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs pharmacological prophylaxis alone

Incidence of PEa (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

IPC plus pharmacological prophylaxis may leads to lower incidence of PEa (early postoperative period) compared with pharmacological prophylaxis alone (low certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs pharmacological prophylaxis alone

Incidence of DVTc (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

IPC plus pharmacological prophylaxis leads to lower incidence of DVTc (early postoperative period) compared with pharmacological prophylaxis alone (high certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs pharmacological prophylaxis alone

Incidence of bleedingd (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

It is very uncertain whether IPC plus pharmacological prophylaxis changes incidence of bleedinge (early postoperative period) compared with pharmacological prophylaxis alone (very low certainty).

1 finding from 1 review

IPC plus pharmacological prophylaxis vs pharmacological prophylaxis alone

Incidence of major bleedingg (early postoperative period) · people undergoing surgery or at risk of developing VTE because of surgery, trauma or ICU stay

It is very uncertain whether IPC plus pharmacological prophylaxis changes incidence of major bleedingg (early postoperative period) compared with pharmacological prophylaxis alone (very low certainty).

1 finding from 1 review