Early childhood caries (ECC) - incidence/risk · Children with exclusively primary dentition (age ≤71 months)
Breastfeeding beyond 24 months is associated with an increased risk (incidence) of early childhood caries versus not breastfeeding at the same age (RR 2.44, 95% CI 1.97 to 3.02; low certainty).
1 finding from 1 review
Early childhood caries (ECC) · Children younger than 71 months (under 6 years)
Breastfeeding for more than 12 months is associated with higher ECC prevalence (low certainty).
1 finding from 1 review
OR 1.86 [1.48, 2.35]
13 studies
Low
Early childhood caries (ECC) · Children younger than 71 months (under 6 years)
Breastfeeding for more than 24 months is associated with higher ECC prevalence (low certainty).
1 finding from 1 review
OR 2.99 [1.03, 8.67]
4 studies
Low
Early childhood caries (ECC) · Children younger than 71 months (under 6 years)
Breastfeeding for 12-24 months is associated with higher ECC prevalence (low certainty).
1 finding from 1 review
PR 3.32 [1.57, 5.07]
2 studies
Low
Early childhood caries (ECC) - incidence/risk · Children younger than 71 months (under 6 years)
Breastfeeding for 12-24 months may not increase ECC risk (low certainty).
1 finding from 1 review
RR 1.21 [0.82, 1.78]
5 studies
Low
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
In 1 study, 115 of 118 children had black stains on teeth treated with SDF; there were no other adverse effects or allergic reactions. In 1 study, the rate of adverse effects reported by caregiver and person who…
3 studies · 482 participants
Very low
Aesthetics · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Ruff 2022 reported that there were no adverse events during the study period; adverse events were not defined by the study authors. Assumed data available for 1398 participants.
1 study · 1398 participants
Very low
Aesthetics · Children and adults (with or without carious lesions)
1 finding from 1 review
1 study reported that 45% of parents were satisfied with appearance of their child's teeth; data not reported by study group. 1 study reported that 1 of 34 caregivers in SDF group were "annoyed with teeth appearance",…
2 studies · 248 participants
Very low
Oral health-related quality of life · Children with dental caries
SDF had no significant effect on oral health-related quality of life versus pooled standard-of-care caries treatments (SMD -0.06, 95% CI -0.20 to 0.08; ungraded).
1 finding from 1 review
Mutans streptococci prevalence (presence/absence) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
It is very uncertain whether chlorhexidine gel (0.12%) changes mutans streptococci prevalence (presence/absence) compared with no treatment (very low certainty).
1 finding from 1 review
Chlorhexidine oral product (one formulation/concentration) vs Another chlorhexidine formulation, concentration or application frequency
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Adverse events · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review
Adverse events (e.g. ulcers, tooth staining) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
1 finding from 1 review
Chlorhexidine mouthrinse vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Chlorhexidine spray vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Chlorhexidine toothpaste vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review
Chlorhexidine chewing gum vs Placebo or no intervention (including routine care)
Outcome not reported · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
The review found no eligible studies for this question.
1 finding from 1 review