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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,173 questions in 89 reviews · Neuromuscular
current versionsNo studies 302 · 25.7%Ungraded 119 · 10.1%Very low 267 · 22.8%Low 239 · 20.4%Moderate 177 · 15.1%High 69 · 5.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Strengthening exercise vs no exercise Change in time taken for 6m comfortable walk (seconds) · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 26 participants | Moderate |
Strengthening exercise vs no exercise Change in isokinetic knee extension torque (Nm) · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 26 participants | Moderate |
Strengthening exercise vs no exercise Change in endurance at 80% MVC (seconds) · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 23 participants | Moderate |
Strengthening exercise vs no exercise Change in isokinetic knee flexion torque (Nm) · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 26 participants | Moderate |
Strengthening exercise vs no exercise Change in maximal isometric voluntary contraction force (Nm) · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 26 participants | Moderate |
Lower limb strengthening and balance exercise vs upper limb strengthening exercise % Change in activities specific balance confidence scale scores ABC scale. Scale from: 0 to 100. · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 16 participants | Moderate |
Home exercise vs no exercise Change in average muscle scores AMS. Scale from: 0 to 10. · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 28 participants | Moderate |
Home exercise vs no exercise Change in left handgrip force (Kg) · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 28 participants | Moderate |
Home exercise vs no exercise Change in right handgrip force (Kg) · patients with people with peripheral neuropathy Exercise for people with peripheral neuropathy (2004) · Cochrane | no estimate extracted | 1 study · 28 participants | Moderate |
Any CNTF vs placebo Deaths · patients with amyotrophic lateral sclerosis or motor neuron disease Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease (2004) · Cochrane | RR 1.07 [0.81, 1.41] | 2 studies · 1300 participants | High |
Any CNTF vs placebo Muscle strength change from baseline value of isometric muscle strength (combination megascore) · patients with amyotrophic lateral sclerosis or motor neuron disease Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease (2004) · Cochrane | no estimate extracted | 2 studies · 1300 participants | High |
Any CNTF vs placebo Respiratory function (FVC %) change from baseline measures of forced vital capacity as a percentage of the predicted value (FVC %) · patients with amyotrophic lateral sclerosis or motor neuron disease Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease (2004) · Cochrane | no estimate extracted | 2 studies · 1300 participants | High |
Any CNTF vs placebo Changes in quality of life (SIP) change in Sickness Impact Profile (SIP) scores (range from 0 = best health to 100 = worst health). · patients with amyotrophic lateral sclerosis or motor neuron disease Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease (2004) · Cochrane | no estimate extracted | 1 study · 503 participants | High |
Any CNTF vs placebo Asthenia · patients with amyotrophic lateral sclerosis or motor neuron disease Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease (2004) · Cochrane | RR 1.02 [0.81, 1.28] | 1 study · 570 participants | High |
Any CNTF vs placebo Nausea · patients with amyotrophic lateral sclerosis or motor neuron disease Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease (2004) · Cochrane | RR 1.35 [0.92, 1.99] | 1 study · 570 participants | High |
Any CNTF vs placebo Increased salivation · patients with amyotrophic lateral sclerosis or motor neuron disease Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease (2004) · Cochrane | RR 1.08 [0.78, 1.5] | 1 study · 570 participants | High |
Prednisone vs prednisone and plasma exchange (Gajdos 1983) Score (MMS) day 30 Plasma exchange for generalised myasthenia gravis (2002) · Cochrane | no estimate extracted | 1 study · 14 participants | Low |
Prednisone vs prednisone and plasma exchange (Gajdos 1983) Score (MMS) month 12 Plasma exchange for generalised myasthenia gravis (2002) · Cochrane | no estimate extracted | 1 study · 14 participants | Low |
IVIg vs plasma exchange Week 1 Plasma exchange for generalised myasthenia gravis (2002) · Cochrane | no estimate extracted | 1 study · 12 participants | Very low |
IVIg vs plasma exchange Week 4 Plasma exchange for generalised myasthenia gravis (2002) · Cochrane | no estimate extracted | 1 study · 12 participants | Very low |
PE vs IVIg Change in score (MMS) day 0 to day 15 Plasma exchange for generalised myasthenia gravis (2002) · Cochrane | no estimate extracted | 1 study · 87 participants | High |
PE vs no plasma exchange before thymectomy (Kamel 2009) Duration of MV (days) Plasma exchange for generalised myasthenia gravis (2002) · Cochrane | no estimate extracted | 1 study · 45 participants | Low |
PE vs no plasma exchange before thymectomy (Kamel 2009) Duration of ICU stay (days) Plasma exchange for generalised myasthenia gravis (2002) · Cochrane | no estimate extracted | 1 study · 45 participants | Low |