Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

764 questions · 795 findings · 110 reviews

No studies found 202 · 25.4%GRADE not reported 100 · 12.6%Very low 225 · 28.3%Low 155 · 19.5%Moderate 85 · 10.7%High 28 · 3.5%

Early ventilation tubes vs watchful waiting

Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether early ventilation tubes changes presence/persistence of OME Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).

1 finding from 1 review

Early ventilation tubes vs watchful waiting

Adverse event: persistent perforation · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether early ventilation tubes changes adverse event: persistent perforation compared with watchful waiting (treatment later if required) (very low certainty).

1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Live birth rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

The review found no eligible studies for this question.

1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Clinical pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

Starting administration of the progestogen earlier probably leads to higher clinical pregnancy rate compared with starting administration of the progestogen later (moderate certainty).

1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Miscarriage · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

It is very uncertain whether starting administration of the progestogen earlier changes miscarriage Rate compared with starting administration of the progestogen later (very low certainty).

1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Cycle cancellation rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

Starting administration of the progestogen earlier probably leads to lower cycle cancellation rate compared with starting administration of the progestogen later (moderate certainty).

1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Endometrial thickness (mm) · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

The review found no eligible studies for this question.

1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

The review found no eligible studies for this question.

1 finding from 1 review