Intervention not reported
Requirement for inotropic support (scale from 0 to 28, days of catecholamine use) · adult (≥ 18 years of age) patients receiving mechanical ventilation (via either an endotracheal tube or a tracheostomy) for acute…
1 finding from 1 review
Intervention not reported
Requirement for renal replacement therapy ( · adult (≥ 18 years of age) patients receiving mechanical ventilation (via either an endotracheal tube or a tracheostomy) for acute…
It is very uncertain whether the intervention changes requirement for renal replacement therapy ( (very low certainty).
1 finding from 1 review
Intervention not reported
Quality of life · adult (≥ 18 years of age) patients receiving mechanical ventilation (via either an endotracheal tube or a tracheostomy) for acute…
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Intervention not reported
Adaptive behavior Measured by: Vineland Adaptive Behavior Scales (parent‐reported scale; mean = 100 (SD = 15); higher score equates to better outcomes) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Adverse effects Measured by: worsening of adaptive behavior or autism symptom severity · patients with young children (less than six years old) with autism spectrum disorders (ASD)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Intelligence Measured by: standardized IQ tests (mean = 100 (SD = 15); higher scores indicate higher IQ) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Communication and language skills: expressive language Measured by: standardized measures of expressive language (higher scores indicate better expressive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Communication and language skills: receptive language Measured by: standardized measures of receptive language (higher scores indicate better receptive language skills) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Intervention not reported
Problem behavior Measured by: standardized parent‐report measures and checklists (lower scores indicate lower levels or less severe problem behavior) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review
Duration of mechanical ventilation · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
ICU mortality · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in ICU mortality compared with usual care (low certainty).
1 finding from 1 review
Hospital mortality · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in hospital mortality compared with usual care (low certainty).
1 finding from 1 review
Duration of ICU stay · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
Length of hospital stay · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
Adverse event ‐ incidence of self‐extubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of self‐extubation (in ICU) compared with usual care (high certainty).
1 finding from 1 review
Adverse event ‐ incidence of reintubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of reintubation (in ICU) compared with usual care (low certainty).
1 finding from 1 review
Incidence of tracheostomy (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in incidence of tracheostomy (in ICU) compared with usual care (low certainty).
1 finding from 1 review
Number of delirium ‐ and coma‐free days (within 28 days) measured by CAM‐ICU or ICDSC · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Ventilator‐free days (within the first 30 days) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review