Findings

What do systematic reviews say?

467 questions · 471 findings · 38 reviews · Airways

No studies found 35 · 7.4%GRADE not reported 27 · 5.7%Very low 31 · 6.6%Low 138 · 29.3%Moderate 178 · 37.8%High 62 · 13.2%

Nausea and vomiting · patients with acute asthma

ICS showed no clear difference in adverse effects ‐ nausea/vomiting compared with placebo (low certainty).

1 finding from 1 review

Early use of inhaled corticosteroids in the emergency department treatment of acute asthma 2012 · Cochrane Headline outcomes only
OR 0.32 [0.03, 3.18]
1 study · 94 participants
Low

Asthma relapse1at 20 to 24 days · predominantly adults with acute asthma following emergency department discharge

Any ICS plus oral corticosteroid showed no clear difference in asthma relapse1at 20 to 24 days compared with oral corticosteroid (high certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 0.68 [0.46, 1.02]
3 studies · 909 participants
High

Hospital admissions · predominantly adults with acute asthma following emergency department discharge

Any ICS plus oral corticosteroid showed no clear difference in hospital admission compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 0.99 [0.39, 2.52]
2 studies · 805 participants
Moderate

Hoarseness at 20 to 24 days · predominantly adults with acute asthma following emergency department discharge

Any ICS plus oral corticosteroid showed no clear difference in hoarseness at 20 to 24 days compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 0.6 [0.36, 1.01]
2 studies · 596 participants
Moderate

Asthma relapse1at 16 to 21 days · patients with acute asthma following emergency department discharge

Any ICS showed no clear difference in asthma relapse1at 16 to 21 days compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 1.26 [0.8, 1.99]
2 studies · 425 participants
Moderate

Hospital admissions · patients with acute asthma following emergency department discharge

Any ICS showed no clear difference in hospital admission compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 0.31 [0.01, 7.95]
3 studies · 254 participants
Moderate

Hoarseness at 16 to 21 days · patients with acute asthma following emergency department discharge

Any ICS showed no clear difference in hoarseness at 16 to 21 days compared with oral corticosteroid (low certainty).

1 finding from 1 review

Inhaled steroids for acute asthma following emergency department discharge 2012 · Cochrane Headline outcomes only
OR 1.62 [0.52, 5.05]
1 study · 412 participants
Low