Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

Xylitol vs control

Cost ‐ not measured · preventing acute otitis media in children up to 12 years of age
3 findings from 1 review

Xylitol vs control

Gastrointestinal adverse events · preventing acute otitis media in children up to 12 years of age

Xylitol showed no clear difference in gastrointestinal‐related adverse events compared with control (moderate certainty).

3 findings from 1 review

Xylitol vs control

Antibiotic administration · preventing acute otitis media in children up to 12 years of age

Xylitol showed no clear difference in antibiotic administration compared with control (moderate certainty).

2 findings from 1 review