Xylitol vs control: Gastrointestinal adverse events
Xylitol showed no clear difference in gastrointestinal‐related adverse events compared with control (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Xylitol vs control Gastrointestinal‐related adverse events · preventing acute otitis media in children up to 12 years of age Xylitol showed no clear difference in gastrointestinal‐related adverse events compared with control (moderate certainty). Xylitol for preventing acute otitis media in children up to 12 years of age (2016) · Cochrane Headline outcomes only | RR 1.04 [0.92, 1.16] | 1 study · 326 participants | Moderate |
Xylitol vs control Gastrointestinal‐related adverse events · preventing acute otitis media in children up to 12 years of age Xylitol showed no clear difference in gastrointestinal‐related adverse events compared with control (moderate certainty). Xylitol for preventing acute otitis media in children up to 12 years of age (2016) · Cochrane Headline outcomes only | RR 1.43 [0.74, 2.75] | 3 studies · 1826 participants | Moderate |
Xylitol vs control Gastrointestinal‐related adverse events · preventing acute otitis media in children up to 12 years of age Xylitol showed no clear difference in gastrointestinal‐related adverse events compared with control (moderate certainty). Xylitol for preventing acute otitis media in children up to 12 years of age (2016) · Cochrane Headline outcomes only | RR 2.82 [0.61, 13] | 1 study · 1277 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Xylitol for preventing acute otitis media in children up to 12 years of age 2016 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.