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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,653 questions in 194 reviews · Gynaecology and Fertility

current versions
No studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Helium thermal coagulator vs electrodiathermy
Quality of life (9 months) – EHP‐30 social support · endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extracted1 study · 119 participantsVery low
Helium thermal coagulator vs electrodiathermy
Quality of life (9 months) – EHP‐30 self‐image · endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extracted1 study · 119 participantsVery low
Helium thermal coagulator vs electrodiathermy
Adverse events · endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extracted1 study · 192 participantsVery low
Laparoscopic treatment vs diagnostic laparoscopy
Overall pain scores unclear measurement instrument (12 months) · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extracted1 study · 16 participantsVery low
Laparoscopic treatment vs diagnostic laparoscopy
Live birth · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extractedNRNo studies
Laparoscopic treatment vs diagnostic laparoscopy
Quality of life EQ‐5D index summary (6 months) · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extracted1 study · 39 participantsLow
Laparoscopic treatment vs diagnostic laparoscopy
Quality of life SF‐12 mental health component (6 months) · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extracted1 study · 39 participantsLow
Laparoscopic treatment vs diagnostic laparoscopy
Quality of life SF‐12 physical health component (6 months) · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
no estimate extracted1 study · 39 participantsLow
Laparoscopic treatment vs diagnostic laparoscopy
Viable intrauterine pregnancy confirmed by ultrasound · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
OR 1.89 [1.25, 2.86]3 studies · 528 participantsModerate
Laparoscopic treatment vs diagnostic laparoscopy
Pregnancy loss: ectopic pregnancy per pregnancy · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
OR 1.18 [0.1, 13.48]1 study · 100 participantsLow
Laparoscopic treatment vs diagnostic laparoscopy
Pregnancy loss: miscarriage per pregnancy · women with endometriosis
Laparoscopic surgery for endometriosis (2020) · Cochrane
OR 0.94 [0.35, 2.54]2 studies · 112 participantsLow
UAE/UACE vs systemic MTX
Treatment success after initial treatment UAE vs systemic MTX · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
RR 1 [0.9, 1.12]1 study · 72 participantsLow
Suction curettage under hysteroscopy vs under ultrasonography
Time to normalize β‐hCG after UAE · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
no estimate extracted1 study · 66 participantsVery low
UAE/UACE vs systemic MTX
Complications UAE vs systemic MTX · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
RR 0.47 [0.13, 1.75]1 study · 72 participantsLow
UAE/UACE vs systemic MTX
Adverse effects UAE vs systemic MTX · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
RR 1.58 [0.41, 6.11]1 study · 72 participantsLow
UAE/UACE vs systemic MTX
Blood loss UAE vs systemic MTX · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
no estimate extracted1 study · 72 participantsModerate
UAE/UACE vs systemic MTX
Time to normalize β‐hCG · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
no estimate extractedNRNo studies
Suction curettage under hysteroscopy vs under ultrasonography
Treatment success after initial treatment after UAE · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
RR 0.91 [0.81, 1.03]1 study · 66 participantsVery low
Suction curettage under hysteroscopy vs under ultrasonography
Complications after UAE · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
RR 4 [0.47, 33.91]1 study · 66 participantsVery low
Suction curettage under hysteroscopy vs under ultrasonography
Adverse effects after UAE · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
RR 3.09 [0.12, 78.7]1 study · 66 participantsVery low
Suction curettage under hysteroscopy vs under ultrasonography
Blood loss · women with CSP
Interventions for non‐tubal ectopic pregnancy (2020) · Cochrane
no estimate extractedNRNo studies
LNG‐IUS vs non‐intrauterine progestogen
Regression of EH; by length of · endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
OR 2.94 [2.1, 4.13]10 studies · 1108 participantsModerate
LNG vs no treatment
Adverse effects associated with hormones · women with endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
no estimate extractedNRNo studies
LNG vs no treatment
Withdrawal secondary to adverse effects · women with endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
no estimate extractedNRNo studies
LNG vs no treatment
Satisfaction · women with endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
no estimate extractedNRNo studies
LNG vs no treatment
Cost of treatment · women with endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
no estimate extractedNRNo studies
LNG‐IUS vs non‐intrauterine progestogen
Regression of EH; by length of · endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
OR 3.8 [1.75, 8.23]1 study · 138 participantsLow
LNG‐IUS vs non‐intrauterine progestogen
Hysterectomy; histologically and non‐histologically indicated · endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
OR 0.26 [0.15, 0.46]4 studies · 452 participantsLow
LNG‐IUS vs non‐intrauterine progestogen
Adverse effects associated with hormones:Bleeding/spotting Nausea Weight gain · endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
OR 2.13 [1.33, 3.43]3 studies · 428 participantsVery low
LNG‐IUS vs non‐intrauterine progestogen
Withdrawal secondary to adverse effects · endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
OR 0.41 [0.12, 1.35]4 studies · 360 participantsLow
LNG‐IUS vs non‐intrauterine progestogen
Satisfaction with treatment · endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
OR 5.28 [2.51, 11.1]2 studies · 202 participantsVery low
LNG vs no treatment
Regression of EH ‐ Short · women with endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
OR 78.41 [22.86, 268.97]1 study · 190 participantsLow
LNG vs no treatment
Adverse effects associated with LNG‐IUS · women with endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
no estimate extractedNRNo studies
LNG vs no treatment
Hysterectomy · women with endometrial hyperplasia
Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia (2020) · Cochrane
no estimate extractedNRNo studies
Embryo culture supernatant injection vs no intervention
Live birth/ongoing pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 1.11 [0.73, 1.7]3 studies · 340 participantsVery low
Embryo culture supernatant vs culture medium injection
Clinical pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 1.09 [0.48, 2.46]1 study · 96 participantsVery low
Embryo culture supernatant vs culture medium injection
Ectopic pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
no estimate extractedNRNo studies
Embryo culture supernatant vs culture medium injection
Multiple pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
no estimate extractedNRNo studies
Embryo culture supernatant vs culture medium injection
Preterm delivery · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
no estimate extractedNRNo studies
Embryo culture supernatant vs culture medium injection
Foetal abnormalities · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
no estimate extractedNRNo studies
Embryo culture supernatant injection vs no intervention
Miscarriage · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 0.89 [0.44, 1.78]4 studies · 430 participantsVery low
Embryo culture supernatant injection vs no intervention
Clinical pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 1.13 [0.8, 1.61]5 studies · 526 participantsVery low
Embryo culture supernatant injection vs no intervention
Ectopic pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 0.32 [0.01, 8.24]2 studies · 250 participantsVery low
Embryo culture supernatant injection vs no intervention
Multiple pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 0.7 [0.26, 1.83]2 studies · 150 participantsVery low
Embryo culture supernatant injection vs no intervention
Preterm delivery · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 0.63 [0.17, 2.42]1 study · 90 participantsVery low
Embryo culture supernatant injection vs no intervention
Foetal abnormalities · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
OR 3.1 [0.12, 79.23]1 study · 60 participantsLow
Embryo culture supernatant vs culture medium injection
Live birth/ongoing pregnancy · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
no estimate extractedNRNo studies
Embryo culture supernatant vs culture medium injection
Miscarriage · Subfertile women undergoing assisted reproduction
Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction (2020) · Cochrane
no estimate extractedNRNo studies
G‐CSF vs no treatment or placebo
Ongoing pregnancy rate per woman randomised · subfertile women undergoing assisted reproduction
Granulocyte‐colony stimulating factor administration for subfertile women undergoing assisted reproduction (2020) · Cochrane
RR 1.62 [0.86, 3.08]1 study · 150 participantsVery low
G‐CSF vs no treatment or placebo
Miscarriage rate per woman randomised · subfertile women undergoing assisted reproduction
Granulocyte‐colony stimulating factor administration for subfertile women undergoing assisted reproduction (2020) · Cochrane
Peto OR 0.4 [0.09, 1.77]2 studies · 291 participantsVery low