Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

Group C other: family treatment vs enhanced care

Satisfaction with treatment: leaving the study early FACT Long‐term · people in the prodromal stage of psychosis

It is very uncertain whether group C other: family treatment changes satisfaction with treatment: leaving the study early FACT Long‐term compared with enhanced care (very low certainty).

1 finding from 1 review

Group C other: integrated treatment vs usual care

Prodromal symptoms: transition to psychosis Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group C other: integrated treatment changes prodromal symptoms: transition to psychosis Endpoint data (events)… compared with standard treatment (very low certainty).

1 finding from 1 review

Omega‐3 vs placebo

Global state: antipsychotic prescription Long‐term (events) · people in the prodromal stage of psychosis

Group A: omega‐3 fatty acids may leads to lower global state: antipsychotic prescription Long‐term (events) compared with placebo (low certainty).

1 finding from 1 review

Group C other: integrated treatment vs usual care

Satisfaction with treatment: leaving the study early Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group C other: integrated treatment changes satisfaction with treatment: leaving the study early Endpoint data… compared with standard treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia: Not improved to a clinically important extent · patients with antipsychotic‐induced TD

The intervention may leads to lower tardive dyskinesia: Not improved to a clinically important extent (low certainty).

1 finding from 1 review

Intervention not reported

Tardive dyskinesia: Deterioration of symptoms · patients with antipsychotic‐induced TD

It is very uncertain whether the intervention changes tardive dyskinesia: Deterioration of symptoms (very low certainty).

1 finding from 1 review

Intervention not reported

Acceptability of treatment: Leaving the study early · patients with antipsychotic‐induced TD

It is very uncertain whether the intervention changes acceptability of treatment: Leaving the study early (very low certainty).

1 finding from 1 review

Intervention not reported

Social confidence, social inclusion, social networks, or personalised quality of life measures · patients with antipsychotic‐induced TD

The review found no eligible studies for this question.

1 finding from 1 review

Anticholinergic medication vs other treatments

Adverse effect: any adverse effects · chronic schizophrenia patients with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether anticholinergic medication changes adverse effect: any adverse effects compared with other treatments (very low certainty).

1 finding from 1 review

Anticholinergic medication vs other treatments

Leaving the study early · chronic schizophrenia patients with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether anticholinergic medication changes acceptability of the treatment: leaving the study early compared with other treatments (very low certainty).

1 finding from 1 review