Number of participants with new demineralised lesions (DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Resin-modified glass ionomer cement for bonding orthodontic brackets showed no clear difference in number of participants with new demineralised lesions (DLs) compared with light-cured composite resin for bonding brackets (low certainty).
1 finding from 1 review
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
It is very uncertain whether 2400 to 2800 ppm F toothpaste changes caries increment, tooth index D(M)FT compared with 1000 to 1250 ppm F toothpaste (very low certainty).
1 finding from 1 review
SMD -0.12 [-0.25, 0.01]
3 studies
Very low
Proportion developing new caries · Adults with mature permanent dentition (aged 18 to 93 years at study start)
The review found no eligible studies for this question.
1 finding from 1 review
Side effects · Adults, 16 years and older (dentate)
1 finding from 1 review
Three studies reported that there were no adverse events, one reported one incidence of aphthous ulcer in irrigator group, one reported oral lacerations but found no difference between the interventions, and one did…
5 studies
GRADE not reported
Cost of materials · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
1 finding from 1 review
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
2400 to 2800 ppm F toothpaste may leads to lower caries increment, surface index D(M)FS compared with 440 to 550 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.29 [-0.49, -0.08]
Studies not reported
Low
Plaque · Adults, 16 years and older (dentate)
It is very uncertain whether flossing plus toothbrushing changes plaque compared with toothbrushing alone (very low certainty).
1 finding from 1 review
Postoperative hypersensitivity (POH), cold response measurement (VAS score) · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
Dental cavity liner (e.g. calcium hydroxide, glass ionomer,… showed no clear difference in postoperative hypersensitivity (POH), cold response measurement (VAS… compared with no liner (resin-based composite bonded directly to the tooth); GRADE not reported.
2 findings from 1 review
MD -0.20 [-0.67, 0.26]
2 studies
GRADE not reported
MD -0.33 [-0.76, 0.11]
2 studies
GRADE not reported
Proportion developing new caries · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1000 to 1250 ppm F toothpaste showed no clear difference in proportion developing new caries compared with non-fluoride (0 ppm F) placebo toothpaste (low certainty).
1 finding from 1 review
Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
1 finding from 1 review
Additional SoF Table 3. Adverse effects: current design of the fluoride glass bead inadequate; high attrition partly due to bead breakages ('an improved method of attachment is needed'). 37 participants (1 RCT, Luther…
1 study · 37 participants
Very low
Side effects · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
1 finding from 1 review
Postoperative hypersensitivity (POH), patient-reported (VAS score) · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
Dental cavity liner (e.g. calcium hydroxide, glass ionomer,… led to lower postoperative hypersensitivity (POH), patient-reported (VAS score) compared with no liner (resin-based composite bonded directly to the tooth); GRADE not reported.
2 findings from 1 review
MD -0.33 [-0.43, -0.23]
1 study
GRADE not reported
MD -0.20 [-0.31, -0.09]
1 study
GRADE not reported
Periodontitis (probing pocket depth) · Adults, 16 years and older (dentate)
1 finding from 1 review
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1450 to 1500 ppm F toothpaste probably leads to lower caries increment, surface index D(M)FS compared with 1000 to 1250 ppm F toothpaste (moderate certainty).
1 finding from 1 review
SMD -0.08 [-0.14, -0.01]
10 studies
Moderate
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1700 to 2200 ppm F toothpaste showed no clear difference in caries increment, tooth index D(M)FT compared with 250 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.23 [-0.5, 0.05]
Studies not reported
Low
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
2400 to 2800 ppm F toothpaste showed no clear difference in caries increment, tooth index D(M)FT compared with 440 to 550 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.2 [-0.46, 0.05]
Studies not reported
Low
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
440 to 550 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with non-fluoride (0 ppm F) placebo toothpaste (low certainty).
1 finding from 1 review
SMD -0.12 [-0.31, 0.07]
2 studies
Low
Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
1 finding from 1 review
SoF 5. Adverse effects: no evidence that either intervention had adverse effects. 173 participants (1 RCT, Benson 2019); certainty LOW.
1 study · 173 participants
Low
Caries increment, tooth index D(M)FT · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1 finding from 1 review
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
1 finding from 1 review