It is very uncertain whether ciclesonide changes patients with exacerbations Number of patients with exacerbations compared with fluticasone (dose ratio 1:2) (very low certainty).
It is very uncertain whether ciclesonide changes adverse events Number of patients with adverse events compared with fluticasone (dose ratio 1:2) (very low certainty).
ICS may leads to lower hospital admission compared with placebo (low certainty).
ICS showed no clear difference in FEV1 at 1 hour compared with placebo (low certainty).
ICS showed no clear difference in FEV1 at 3 to 4 hours compared with placebo (moderate certainty).
ICS showed no clear difference in adverse effects ‐ nausea/vomiting compared with placebo (low certainty).