Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

558 questions · 704 findings · 64 reviews · Dental caries

No studies found 91 · 12.9%GRADE not reported 441 · 62.6%Very low 76 · 10.8%Low 73 · 10.4%Moderate 21 · 3%High 2 · 0.3%

ART using glass ionomer cement (GIC) vs Amalgam restoration

Restoration failure (permanent, immature teeth) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) led to higher restoration failure (permanent, immature teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

ART using composite resin vs Conventional treatment using composite resin

Restoration failure (primary dentition) · Children with carious primary teeth

It is very uncertain whether ART using composite resin changes restoration failure (primary dentition) compared with conventional treatment using composite resin (very low certainty).

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Pain (permanent, immature teeth) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) led to lower pain (permanent, immature teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Restoration failure (permanent dentition) · People with dental caries in primary teeth (mainly children)

The review found no eligible studies for this question.

1 finding from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Restoration failure (primary dentition) · People with dental caries in primary teeth (mainly children)

ART using high-viscosity glass ionomer cement (H-GIC), hand… may leads to higher restoration failure (primary dentition) compared with conventional treatment using H-GIC (rotary instruments) (low certainty).

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Participant experience (co-operation during procedure) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)
1 finding from 1 review

Higher drinking-water fluoride exposure vs Lower water fluoride concentration (concurrent control)

Dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations

Higher water fluoride concentration (fluoridated water; natural or… may leads to higher dental fluorosis of aesthetic concern (Dean's Index, TFI, TSIF) compared with lower water fluoride concentration (concurrent control) (low certainty).

1 finding from 1 review

Higher drinking-water fluoride exposure vs Lower water fluoride concentration (concurrent control)

Adverse effects: dental fluorosis · Populations of all ages (mostly children) exposed to drinking water with differing fluoride concentrations

Higher water fluoride concentration (fluoridated water; natural or… may leads to higher dental fluorosis of any level (all severities) compared with lower water fluoride concentration (concurrent control) (low certainty).

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Secondary caries · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Patient's view and satisfaction with the treatment · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Compomer (Dyract) vs Amalgam (Tytin)

Secondary caries · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

Compomer (Dyract) showed no clear difference in secondary caries at 24 months compared with amalgam (Tytin); GRADE not reported.

1 finding from 1 review

Resin-modified glass ionomer (Vitremer) vs Amalgam restoration

Marginal integrity, wear, surface texture, staining and secondary caries (Ryge criteria) at 6-12 months · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free
1 finding from 1 review
  • Marginal integrity, wear, surface texture, axial contour, staining and secondary caries (Ryge criteria) at 6 and 12 months: odds ratios not estimable - no events recorded, implying equal performance of the two materials.
    1 study · 60 participants
    GRADE not reported

Fluoride gel combined with fluoride mouthrinse vs Fluoride gel

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride gel combined with fluoride mouthrinse showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride gel alone; GRADE not reported.

1 finding from 1 review

Fluoride varnish combined with fluoride toothpaste vs Fluoride varnish

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride varnish combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride varnish alone; GRADE not reported.

1 finding from 1 review

Fluoride varnish combined with fluoride toothpaste vs Fluoride toothpaste alone

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride varnish combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride toothpaste alone; GRADE not reported.

1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride mouthrinse

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride mouthrinse combined with fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs / leaving study early) compared with fluoride mouthrinse alone; GRADE not reported.

1 finding from 1 review