Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

957 questions · 979 findings · 250 reviews

No studies found 159 · 16.2%GRADE not reported 75 · 7.7%Very low 264 · 27%Low 303 · 30.9%Moderate 138 · 14.1%High 40 · 4.1%

Film dressing vs exposed wound

SSI Assessment method: undefined method · surgical wounds resulting from clean surgery and healing by primary intention

It is very uncertain whether film dressing changes SSI Assessment method: undefined method compared with exposed wound (very low certainty).

1 finding from 1 review

Silver dressing vs exposed wound

SSI Assessment method: CDC definition of SSI · surgical wounds resulting from a range of surgical procedures with some risk of contamination healing by primary intention

It is very uncertain whether silver dressing changes SSI Assessment method: CDC definition of SSI compared with exposed wound (very low certainty).

1 finding from 1 review

Impregnated catheters vs non‐impregnated catheters

Adverse effects (combined) Clinical assessment · Adult patients who required central venous catheters

Impregnated catheters showed no clear difference in adverse effects (combined) Identified by clinical assessment compared with non‐impregnated catheters (high certainty).

1 finding from 1 review

MAL‐PDT vs red light only

Investigator's global assessment (IGA) of improvement Treatment 'success' as defined by IGA score decrease5 · Moderate and severe acne vulgaris

MAL‐PDT probably leads to higher investigator's global assessment (IGA) of improvement Treatment… compared with red light only (moderate certainty).

1 finding from 1 review
  • Light therapies for acne 2016 · Cochrane Headline outcomes only
    RR 1.74 [1.11, 2.74]
    3 studies · 360 participants
    Moderate

ALA‐PDT vs blue light only

Participant's global assessment of improvement Non‐standardised scale5 · Moderate and severe acne vulgaris

ALA‐PDT showed no clear difference in participant's global assessment of improvement Non‐standardised scale5 compared with blue light only (low certainty).

1 finding from 1 review

ALA‐PDT vs blue light only

Investigator's global assessment (IGA) of improvement Treatment 'success' as defined by IGA score decrease5 · Moderate and severe acne vulgaris

ALA‐PDT showed no clear difference in investigator's global assessment (IGA) of improvement Treatment… compared with blue light only (low certainty).

1 finding from 1 review

MAL‐PDT vs red light only

Paticipant's global assessment of improvement ‐ Not measured · Moderate and severe acne vulgaris

The review found no eligible studies for this question.

1 finding from 1 review
  • Light therapies for acne 2016 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Specific allergen immunotherapy vs no immunotherapy

Investigator‐ or physician‐rated global assessment of disease severity · adults and children with atopic eczema and inhalant allergen sensitisation

It is very uncertain whether specific allergen immunotherapy changes investigator‐ or physician‐rated global assessment of disease severity compared with no immunotherapy (very low certainty).

1 finding from 1 review

Oral midazolam vs chloral hydrate

Level of sedation on a sedation assessment scale · children requiring sedation before procedures that require motion control, including echocardiography, lumbar puncture, micturating…
1 finding from 1 review

Oral midazolam vs placebo

Level of sedation on a sedation assessment scale · children requiring sedation before micturating cystourethrograms and Kirschner wire removal and adults undergoing flexible sigmoidoscopy
1 finding from 1 review

Chlorhexidine vs povidone‐iodine

All‐cause mortality ‐ Chlorhexidine in aqueous solution versus povidone‐iodine in aqueous solution Clinical assessment · patients with a central venous catheter

Chlorhexidine showed no clear difference in all‐cause mortality ‐ Chlorhexidine in aqueous solution versus… compared with povidone‐iodine (low certainty).

1 finding from 1 review

Chlorhexidine vs povidone‐iodine

All‐cause mortality ‐ Chlorhexidine in alcohol versus povidone‐iodine in aqueous solution Clinical assessment · patients with a central venous catheter

Chlorhexidine showed no clear difference in all‐cause mortality ‐ Chlorhexidine in alcohol versus… compared with povidone‐iodine (low certainty).

1 finding from 1 review

Intervention not reported

Clinician assessment practices (1 year) · Carers of elderly persons with a responsibility for detecting abuse
1 finding from 1 review

Intervention not reported

Global assessment of treatment success Satisfactory pace of recovery · people following primary uncemented THA

It is very uncertain whether the intervention changes global assessment of treatment success Satisfactory pace of recovery (very low certainty).

1 finding from 1 review