Intervention not reported
Mean change from baseline in 6MWT (metres) · adults and children with mucopolysaccharidosis I
1 finding from 1 review
Intervention not reported
Infusion‐related reactions (number of participants with one or more reaction) · adults and children with mucopolysaccharidosis I
The intervention showed no clear difference in infusion‐related reactions (number of participants with one or more… (low certainty).
1 finding from 1 review
Intervention not reported
Antibody production: number of participants developing IgG antibodies · adults and children with mucopolysaccharidosis I
It is very uncertain whether the intervention changes antibody production: number of participants developing IgG antibodies (very low certainty).
1 finding from 1 review
Intervention not reported
Quality of life · adults and children with mucopolysaccharidosis I
1 finding from 1 review
Intervention not reported
Mortality: number of deaths · adults and children with mucopolysaccharidosis I
1 finding from 1 review
50% or greater reduction in seizure frequency · patients between 3 to 15 months of age with West syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Complete cessation of seizures 9 days · patients between 3 to 15 months of age with West syndrome
It is very uncertain whether sulthiame add‐on changes complete cessation of seizures during compared with placebo (very low certainty).
1 finding from 1 review
Seizure frequency · patients between 3 to 15 months of age with West syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Time to treatment withdrawal · patients between 3 to 15 months of age with West syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Number experiencing adverse effects · patients between 3 to 15 months of age with West syndrome
It is very uncertain whether sulthiame add‐on changes adverse effects: total number of participants experiencing one or… compared with placebo (very low certainty).
1 finding from 1 review
Somnolence · patients between 3 to 15 months of age with West syndrome
It is very uncertain whether sulthiame add‐on changes adverse effects: somnolence compared with placebo (very low certainty).
1 finding from 1 review
Quality of life · patients between 3 to 15 months of age with West syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Dry eye symptoms, measured using the OSDI score (ranging from 0 to 100 units, with a reduction in scores indicating clinical improvement) at 1‐month (with actual · people with dry eye
1 finding from 1 review
Ocular surface staining · people with dry eye
1 finding from 1 review
Aqueous tear production · people with dry eye
1 finding from 1 review
Tear film stability · people with dry eye
1 finding from 1 review
Frequency of artificial tear usage at 6 months · people with dry eye
1 finding from 1 review
Conjunctival goblet cell density (cells per unit) at 6 months · people with dry eye
1 finding from 1 review
Treatment related adverse events, · people with dry eye
1 finding from 1 review
Serological cure assessed by decrease in the CSF VDRL titre · people with neurosyphilis
1 finding from 1 review