Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,734 questions · 15,288 findings · 893 reviews

No studies found 3,864 · 25.3%GRADE not reported 2,222 · 14.5%Very low 3,868 · 25.3%Low 3,280 · 21.5%Moderate 1,676 · 11%High 378 · 2.5%

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Rubber dam vs No rubber dam

Reduction in level of contamination in aerosols (CFU) during restorative procedures at 1 metre from mouth (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

Rubber dam led to lower reduction in level of contamination in aerosols (CFU) during… compared with no rubber dam; GRADE not reported.

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Topical triamcinolone acetonide vs Hyaluronic acid gel

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical triamcinolone acetonide showed no clear difference in pain (mean score) compared with hyaluronic acid gel; GRADE not reported.

1 finding from 1 review

Integrated Chinese and Western medicine (incl. oral prednisone) vs Western medicine (incl. oral prednisone)

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
1 finding from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) at less than 1 foot from oral cavity (CCTs) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

High-volume evacuation (HVE) showed no clear difference in reduction in level of contamination in aerosols (CFU) at less than 1… compared with no HVE; GRADE not reported.

1 finding from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling and air polishing at more than 1 foot from oral cavity (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with no HVE (very low certainty).

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs other local anaesthetic

Adverse effects · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Topical triamcinolone acetonide vs Cryotherapy

Pain (mean score, split-mouth) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical triamcinolone acetonide changes pain (mean score, split-mouth) compared with cryotherapy (very low certainty).

1 finding from 1 review

The wand (computer-controlled LA delivery system) vs other local anaesthetic

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clobetasol propionate 0.025% microspheres vs Clobetasol propionate 0.025% ointment

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate 0.025% microspheres led to higher pain (mean score) compared with clobetasol propionate 0.025% ointment; GRADE not reported.

1 finding from 1 review

Topical clobetasol propionate vs Topical ciclosporin

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical clobetasol propionate changes clinical resolution compared with topical ciclosporin (very low certainty).

1 finding from 1 review

Camouflage syringe vs Conventional syringe

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour (crying) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether camouflage syringe changes self- or observational assessment of intraoperative… compared with conventional syringe (very low certainty).

1 finding from 1 review

Pre-cooling of the injection site vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
1 finding from 1 review

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Antimicrobial coolant A (chlorhexidine) vs Distilled water coolant

Reduction in level of contamination in aerosols (CFU): chlorhexidine coolant vs distilled water during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether chlorhexidine coolant changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with distilled water coolant (very low certainty).

1 finding from 1 review