Topical clobetasol propionate vs Topical ciclosporin: Clinical resolution
- Population
- People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
- Intervention
- Topical clobetasol propionate
- Comparison
- Topical ciclosporin
- Outcome
- Clinical resolution
It is very uncertain whether topical clobetasol propionate changes clinical resolution compared with topical ciclosporin (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical clobetasol propionate vs Topical ciclosporin Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment · 3-8 weeks It is very uncertain whether topical clobetasol propionate changes clinical resolution compared with topical ciclosporin (very low certainty). Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane All outcomes | RR 3.16 [1.00, 9.93] | 1 study · 39 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes | 2019-02 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Topical clobetasol propionate vs Topical tacrolimus · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.