Question · asked by 1 review

Dexamethasone ointment vs Amlexanox paste: Pain resolution

Population
People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Intervention
Dexamethasone ointment
Comparison
Amlexanox paste
Outcome
Pain resolution

It is very uncertain whether dexamethasone ointment changes pain resolution compared with amlexanox paste (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Dexamethasone ointment vs Amlexanox paste
Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
It is very uncertain whether dexamethasone ointment changes pain resolution compared with amlexanox paste (very low certainty).
Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane All outcomes
RR 0.75 [0.34, 1.66]1 study · 36 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral lichen planus: corticosteroid therapies
2020 · Cochrane All outcomes
2019-02Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.