MAL‐PDT vs surgical excision
MAL‐PDT showed no clear difference in pain compared with surgical excision (low certainty).
- RR 2.2 [0.6, 8.03]1 study · 101 participantsLow
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MAL‐PDT showed no clear difference in pain compared with surgical excision (low certainty).
MAL‐PDT probably leads to higher early treatment failure compared with surgical excision (moderate certainty).
Imiquimod cream probably leads to lower recurrence at 3 years compared with MAL‐PDT (moderate certainty).
Imiquimod cream showed no clear difference in cosmetic outcome (excellent/good) compared with MAL‐PDT (moderate certainty).
Imiquimod cream probably leads to lower pain (moderate/severe) compared with MAL‐PDT (moderate certainty).
Imiquimod cream showed no clear difference in early treatment failure compared with MAL‐PDT (moderate certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Imiquimod probably leads to higher recurrence at 3 years compared with surgical excision (moderate certainty).
Imiquimod may leads to higher cosmetic outcome (good/excellent) compared with surgical excision (low certainty).
Imiquimod showed no clear difference in pain (moderate/severe) compared with surgical excision (low certainty).
It is very uncertain whether psychological therapy changes adverse events: death ‐ at end of treatment (Analysis 2.16) compared with usual care and/or attention control (very low certainty).
The review found no eligible studies for this question.
Oral health care intervention showed no clear difference in presence of related infection: pneumonia (Analysis 2.1) compared with placebo (low certainty).