Hyperkalaemia · patients with chronic heart failure with preserved ejection fraction
Angiotensin receptor neprilysin inhibitors (ARNIs) showed no clear difference in hyperkalaemia Range of compared with usual care (moderate certainty).
1 finding from 1 review
All‐cause mortality (RR) Range of · patients with chronic heart failure with preserved ejection fraction
Angiotensin receptor neprilysin inhibitors (ARNIs) leads to lower all‐cause mortality (RR) Range of compared with usual care (high certainty).
1 finding from 1 review
Quality of life Range of · patients with chronic heart failure with preserved ejection fraction
1 finding from 1 review
no estimate extracted
118 participants
High
All‐cause mortality · Older adults, 50 years and older
Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in all‐cause mortality compared with continuation (low certainty).
1 finding from 1 review
Fatal or nonfatal myocardial infarction · Older adults, 50 years and older
It is very uncertain whether discontinuation by no treatment/placebo of antihypertensives changes myocardial infarction (fatal and nonfatal) compared with continuation (very low certainty).
1 finding from 1 review
Hospital admissions · Older adults, 50 years and older
Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in hospitalisation compared with continuation (low certainty).
1 finding from 1 review
Stroke (fatal + nonfatal + TIA) · Older adults, 50 years and older
Discontinuation by no treatment/placebo of antihypertensives showed no clear difference in stroke (fatal + nonfatal + TIA) compared with continuation (low certainty).
1 finding from 1 review
Systolic blood pressure · Older adults, 50 years and older
1 finding from 1 review
Diastolic blood pressure · Older adults, 50 years and older
1 finding from 1 review
Adverse drug reactions and adverse drug withdrawal reactions (adverse reactions) · Older adults, 50 years and older
1 finding from 1 review
Falls ‐ not reported · Older adults, 50 years and older
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause death · people with diabetes and kidney disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cardiovascular mortality · people with diabetes and kidney disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Doubling of SCr · people with diabetes and kidney disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fatal or nonfatal stroke · people with diabetes and kidney disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fatal or nonfatal myocardial infarction · people with diabetes and kidney disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Micro‐ to macroalbuminuria · people with diabetes and kidney disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Micro‐ to normoalbuminuria · people with diabetes and kidney disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death (all causes) · people with diabetes and kidney disease
1 finding from 1 review
Cardiovascular mortality · people with diabetes and kidney disease
1 finding from 1 review