Findings

What do systematic reviews say?

462 questions · 474 findings · 56 reviews · Eyes and Vision

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No studies found 147 · 31%GRADE not reported 15 · 3.2%Very low 89 · 18.8%Low 157 · 33.1%Moderate 52 · 11%High 14 · 3%

IStent (or iStent inject) vs medical therapy

Health‐related quality of life · open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IStent (or iStent inject) vs medical therapy

Intraoperative complications · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 101 participants
GRADE not reported

IStent (or iStent inject) vs medical therapy

Postoperative complications · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 286 participants
GRADE not reported

IStent in combination with phacoemulsification vs phacoemulsification alone

Mean change in number of IOP‐lowering drops from baseline · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 282 participants
Very low

IStent in combination with phacoemulsification vs phacoemulsification alone

Difference in mean IOP from baseline at < 6 months · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 284 participants
Very low

IStent in combination with phacoemulsification vs phacoemulsification alone

Health‐related quality of life · open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IStent in combination with phacoemulsification vs phacoemulsification alone

Intraoperative complications · open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IStent in combination with phacoemulsification vs phacoemulsification alone

Postoperative complications · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 334 participants
GRADE not reported

IStent (or iStent inject) vs medical therapy

Proportion of participants who were drop‐free · open‐angle glaucoma

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 286 participants
Very low

IStent (or iStent inject) vs medical therapy

Mean change in number of IOP‐lowering drops from baseline · open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Ab interno trabecular bypass surgery with iStent for open‐angle glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs vs corticosteroids

Intraocular inflammation measured by anterior chamber cell and flare 1 week · people who received phacoemulsification

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 174 participants
Moderate

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Proportion of participants with best‐corrected visual acuity of 20/40 1 week · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Proportion of participants with cystoid macular edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs plus corticosteroids may leads to lower proportion of participants with cystoid macular edema 1 week compared with corticosteroids alone (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
RR 0.17 [0.03, 0.97]
2 studies · 220 participants
Low

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Time to cessation of treatment · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Adverse events · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Economic outcomes · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs vs corticosteroids

Intraocular inflammation measured by proportion of participants with corneal edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs showed no clear difference in intraocular inflammation measured by proportion of participants with… compared with corticosteroids (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
RR 0.77 [0.26, 2.29]
1 study · 114 participants
Low

Summary of findings for NSAIDs vs corticosteroids

Proportion of participants with best‐corrected visual acuity of 20/40 1 week · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs vs corticosteroids

Proportion of participants with cystoid macular edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs may leads to lower proportion of participants with cystoid macular edema 1 week compared with corticosteroids (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
RR 0.26 [0.17, 0.41]
4 studies · 291 participants
Low

Summary of findings for NSAIDs vs corticosteroids

Time to cessation of treatment · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found