Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Hydrosurgery vs conventional 'open' surgical debridement

Post-operative infection · acute partial‐thickness burns prior to skin grafting

It is very uncertain whether hydrosurgery changes postoperative infection (number of participants with post‐operative… compared with conventional debridement (very low certainty).

1 finding from 1 review

Open surgery vs ERCP

Retained stones after primary intervention · with common bile duct stones

Open surgery probably leads to lower retained stones after primary intervention compared with ERCP (moderate certainty).

1 finding from 1 review

Electrical stimulation plus surgery vs surgery

Cure: number of women with self‐reported continence · women with stress urinary incontinence

It is very uncertain whether electrical stimulation plus surgery changes cure: number of women with self‐reported continence compared with surgery (very low certainty).

1 finding from 1 review

Electrical stimulation plus surgery vs surgery

Improvement: number of women with self‐reported improvement in SUI (cured or improved) · women with stress urinary incontinence

It is very uncertain whether electrical stimulation plus surgery changes improvement: number of women with self‐reported improvement in SUI… compared with surgery (very low certainty).

1 finding from 1 review

Neuronavigation image‐guided surgery vs surgery

Overall survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Neuronavigation image‐guided surgery vs surgery

Progression‐free survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Neuronavigation image‐guided surgery vs surgery

Quality of life · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Neuronavigation image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Autofluorescence-guided bone surgery vs Tetracycline fluorescence-guided bone surgery

Healing of MRONJ (mucosal integrity) · People with MRONJ referred for surgical treatment

It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).

1 finding from 1 review

Platelet-rich fibrin after bone surgery vs Bone surgery alone

Healing of MRONJ (mucosal integrity, absence of infection, and no re-intervention) · People with established (manifest) MRONJ

It is very uncertain whether platelet-rich fibrin after bone surgery changes healing of MRONJ (mucosal integrity, absence of infection, and no… compared with bone surgery alone (very low certainty).

1 finding from 1 review

Decompressive surgery plus radiotherapy vs radiotherapy

Ambulation · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

Decompressive surgery plus radiotherapy may leads to higher ambulation Immediately after completing RT compared with radiotherapy (low certainty).

1 finding from 1 review