Specificity · Extracted molar teeth of adults with resin composite approximal restorations (in vitro; secondary root caries; Switzerland)
1 finding from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
Sealant may be more effective than no treatment for arrest or reversal of approximal carious lesions (RR 2.41, 95% CI 1.26 to 4.58; low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
38% SDF solution (applied annually) may not differ from 5% NaF varnish for arrest or reversal of root carious lesions (RR 0.64, 95% CI 0.04 to 9.66; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
0.2% NaF mouthrinse + supervised toothbrushing may not differ from Sealant for arrest or reversal of occlusal carious lesions (RR 0.98, 95% CI 0.84 to 1.14; low certainty).
1 finding from 1 review
Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces)
One review reported SDF may reduce progression of root caries, with no numeric result (ungraded).
3 findings from 1 review
One systematic review found that SDF can be efficacious to decrease progression of root carious lesions (no numeric results reported) [24].
Studies not reported
GRADE not reported
Prevented Fraction 100–725
2 studies
GRADE not reported
One low risk of bias systematic review reported that 38% SDF was significantly more effective than placebo in arresting root carious lesions (pooled results were not calculated) [31].
Studies not reported
GRADE not reported
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
Sealant was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 1.98, 95% CI 1.61 to 2.44; moderate certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
1% chlorhexidine + 1% thymol varnish may not differ from 38% SDF + potassium iodide solution (applied annually) for arrest or reversal of root carious lesions (RR 0.71, 95% CI 0.11 to 4.45; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
38% SDF solution (applied annually) may not differ from no treatment for arrest or reversal of root carious lesions (RR 1.92, 95% CI 0.52 to 6.87; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
1.23% APF gel was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 2.13, 95% CI 1.79 to 2.54; moderate certainty).
1 finding from 1 review
Root carious lesions prevention · Older adults with root carious lesions (exposed root surfaces)
38% silver diamine fluoride reduced root-caries increment (DMFRS/DFRS) versus placebo, MD −0.33 (95% CI −0.39 to −0.28) (ungraded).
3 findings from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
5% NaF varnish may not differ from Resin infiltration for arrest or reversal of approximal carious lesions (RR 1.09, 95% CI 0.32 to 3.65; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated facial/lingual carious lesions · Children and adults with noncavitated carious lesions on facial/lingual surfaces (primary and permanent teeth)
10% CPP-ACP cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice) may not differ from Placebo cream (+ 900-ppm NaF mouthrinse + 1,000-ppm NaF dentifrice) for arrest or reversal of facial/lingual carious lesions (RR 1.28, 95% CI 0.97 to 1.68; low certainty).
3 findings from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
5% NaF varnish may not differ from Resin infiltration + 5% NaF varnish for arrest or reversal of approximal carious lesions (RR 0.5, 95% CI 0.18 to 1.37; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
38% SDF solution (applied annually) may not differ from 5,000-ppm F (1.1% NaF) toothpaste or gel for arrest or reversal of root carious lesions (RR 0.72, 95% CI 0.18 to 2.95; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
5% NaF varnish may not differ from 5,000-ppm F (1.1% NaF) toothpaste or gel for arrest or reversal of root carious lesions (RR 1.13, 95% CI 0.1 to 13.12; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated approximal carious lesions · Children and adults with noncavitated carious lesions on approximal surfaces (primary and permanent teeth)
5% NaF varnish may not differ from Sealant for arrest or reversal of approximal carious lesions (RR 0.95, 95% CI 0.38 to 2.41; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
38% SDF + potassium iodide solution (applied annually) may not differ from no treatment for arrest or reversal of root carious lesions (RR 2.36, 95% CI 0.66 to 8.42; very low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
5% NaF varnish was probably less effective than Resin infiltration + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.62, 95% CI 0.46 to 0.83; moderate certainty).
1 finding from 1 review
Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)
1.23% APF gel may not differ from Sealant for arrest or reversal of occlusal carious lesions (RR 1.08, 95% CI 0.82 to 1.41; low certainty).
1 finding from 1 review
Arrest or reversal of noncavitated and cavitated root carious lesions · Adults (including institutionalized/older adults) with noncavitated and cavitated carious lesions on root surfaces (permanent teeth)
5,000-ppm F (1.1% NaF) toothpaste or gel may be more effective than no treatment for arrest or reversal of root carious lesions (RR 2.62, 95% CI 1.49 to 4.63; low certainty).
1 finding from 1 review