Question · asked by 1 review
38% silver diamine fluoride vs placebo: Root carious lesions arrest
- Population
- Older adults with root carious lesions (exposed root surfaces)
- Intervention
- 38% silver diamine fluoride
- Comparison
- placebo
- Outcome
- Root carious lesions arrest
One review reported SDF may reduce progression of root caries, with no numeric result (ungraded).
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
38% silver diamine fluoride vs Placebo Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces) One review reported SDF may reduce progression of root caries, with no numeric result (ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | One systematic review found that SDF can be efficacious to decrease progression of root carious lesions (no numeric results reported) [24]. | Not reported | GRADE not reported |
38% silver diamine fluoride vs Placebo Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces) Reported prevented fractions for 38% SDF versus placebo for root-caries arrest ranged 100 to 725% (one high-risk review, two studies; ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | Prevented Fraction 100–725 | 2 studies | GRADE not reported |
38% silver diamine fluoride vs Placebo Root carious lesions arrest · Older adults with root carious lesions (exposed root surfaces) A low-risk-of-bias review found 38% SDF significantly more effective than placebo for arresting root caries, with no pooled estimate (ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | One low risk of bias systematic review reported that 38% SDF was significantly more effective than placebo in arresting root carious lesions (pooled results were not calculated) [31]. | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Silver diamine fluoride for managing carious lesions: an umbrella review. 2019 All outcomes | June 2018 | 15 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.